Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17810 Saracatinib GSE70138 MCF10A Human 3h 3.33uM EID0022
Types Number Response transcription factors
Up-regulation 246 ZNF226; HDAC6; SKI; SAP30; SAFB; ZNF107; KLF2; PIAS2; ZNF721; POU4F1; SMARCA2; KDM5A; PIR; ARID4A; TRIM16; TCF7; MBD2; LIMD1; NSD1; HOXC5; RORA; SND1; ZMYM2; ING2; ZNF236; NCOA6; HR; RNF111; SREBF2; HOXC6; GATA2; LPIN2; BBX; HOXA1; PBRM1; ASCL1; SIAH2; NCOA1; NR1D2; NANOG; PIAS3; NFAT5; RBBP7; DMRT1; KLF9; ZMIZ1; ZBTB40; NFATC1; POU5F1B; PHOX2B; ETS2; PCBD1; ZHX3; EBF2; ING1; SIM2; KMT2B; DNAJC1; DNMT3B; TRIP4; HCFC2; RREB1; EN2; TCF4; GLI2; NFX1; ZNF136; ZNF652; RNF141; ANKRD1; ZMIZ2; LHX2; SOX10; BRCA1; ZNF492; TMF1; ARNTL; ZNF286A; NFIL3; IRF7; UBTF; DMTF1; ZNF430; MED4; TRIM25; TRIM22; DDX54; CDK2; MEOX2; POU4F2; YAF2; MBD1; EGR3; FOXO1; BCL11B; ARID5B; SOX13; WHSC1L1; CREB5; LMCD1; TBPL1; FOXE1; EZH1; SSX1; OVOL1; DDX5; POU6F1; ZBTB25; TOPORS; USF2; COPS2; PHF8; HOXC4; SAP18; GATA4; GFI1; EYA2; PPP1R13L; JAK2; ARNTL2; FOXJ1; TAF1; DDX17; CREM; ID2; ZSCAN18; MYCN; LHX6; TEAD1; RBL2; ZNF770; PAWR; ZIM2; CBFA2T3; ZNF160; NPM1; AFF2; ZNF24; BARX2; PGR; ARID3A; PSMC3; MAFB; VGLL4; SMAD5; EP400; STAT2; NRBF2; ZNF426; SMARCA4; TFAP2C; PRDM1; AFF1; PRKDC; IRF8; OLIG2; MAX; TSC22D2; ZNF532; EDF1; ZNF529; NR1H2; TBX3; ZNF816; KAT6A; XBP1; HHEX; CTNNB1; ZNF701; BANP; MYBL1; IFNB1; AES; MSX1; KDM4C; ZNF224; ELF1; MYT1L; NCOA3; ZNF264; ELF5; ATF3; KLF4; IRX5; ZBTB16; ZNF175; KLF6; GATAD2A; INSM1; ZEB2; ZNF536; KDM2A; MNDA; ECD; HLX; RFX5; RBM14; SPEN; NCOA4; BTG1; HSBP1; ZNF22; ZBTB38; NR0B1; PCGF2; REPIN1; FOSB; MAGED1; ZNF611; CREBL2; STAT5A; ZBTB18; PHIP; NKX2-2; CREB3L1; JARID2; FOXN3; MNAT1; NUP62; CEBPZ; ZNF589; TXNIP; PSIP1; SOX4; RBBP4; SMAD3; PURA; HOXA5; ZIC1; SNAI2; NEUROD1; ZFP36L2; NR5A2; TCEA1; SOX17; PITX1; EED; HMG20B; BMI1; HIRA; AEBP1; DLX5; MYRF; BCL11A; TWIST1; LEF1
Down-regulation 166 FOSL1; PLAGL2; ATF2; TEAD4; TCEA2; ARNT2; MECOM; SUZ12; PBX3; PAXBP1; ERCC3; BCL6; MED13; SUPT4H1; ZNF473; NFIC; RXRA; SIX2; TGS1; THAP4; CIZ1; PCGF1; ZNF3; HOXD3; SMARCD3; MED17; ZFP36L1; EWSR1; MYF6; HIF1A; ID1; SUPT6H; ERBB4; SUMO1; ELF4; ZNF468; BTF3; ATF5; ZNF593; PBX2; HOXD10; CDK9; GMNN; CCNC; ZNF7; RAD21; SP140L; HDGF; TRAK1; YAP1; USP21; ZNF304; PMS1; BRD4; FOXF2; MED21; KLF7; SP3; ZNF250; CBFA2T2; SOX11; NFE2L2; RERE; TRIP6; ZNF217; SRCAP; SMAD1; CREG1; WT1; NR2F1; TSG101; LITAF; CARM1; EZH2; ZBTB11; NFKB1; ETV4; SIX1; ENY2; ZBED4; ZNF211; NFATC4; MNT; AHR; ZSCAN32; ZNF557; WWC1; CHD9; RBBP8; STAT1; TOX3; WWTR1; BATF3; RFXANK; PIAS4; ATN1; ETS1; HBP1; CHD8; SLC2A4RG; TCF3; RBFOX2; GLI3; TCF21; BCL10; UBE2L3; ZNF195; HOXB6; PRPF6; NR2F2; MECP2; RYBP; TGFB1; CTBP2; ZNF12; SNAPC4; ZNF232; ATF4; ZBED2; ADNP; DDIT3; RNF4; HOXD1; MXI1; TAF10; CITED2; FOSL2; ZNF189; OSR2; CNOT2; ZMYND8; ZNF43; ZNF467; TLE1; NR4A3; CCNH; MEIS1; KLF11; FOXA1; EHF; MYCL; RNF10; TOX; SSBP2; CRYM; SHOX2; CTBP1; KLF1; APEX1; TCF7L2; TBX2; FOXG1; KLF5; ZEB1; PBX1; SOX9; CREB1; SUB1; SCAND1; SATB1; HOXB2; FOXF1; FOS; TRIB3; ZNF91; MEIS2