Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17809	Saracatinib	GSE70138	MCF10A	Human	3h	10uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	GATA3; RORA; PIR; PIAS3; TSC22D3; SAP30; RBPMS; FOXC1; ZNF768; SP110; BBX; NFIL3; ZKSCAN5; TAF12; PCGF2; HOXC10; ZNF200; EYA2; KLF9; CREBZF; BAZ1B; CSDE1; ZBTB25; ZNF227; BRCA1; NFE2L1; ZBTB16; ID2; MYBL2; CDK7; ZNF14; EYA1; ZNF226; FOXN3; NR2F2; ING2; ZNF148; RBBP7; IRX5; SFMBT1; RNF111; POU4F1; ZNF813; KLF2; TLE2; AFF1; TRIP4; SMARCD2; IRF2; TEAD1; ZBTB14; LMO1; DNAJC1; ELF5; BRD8; ZNF205; ZNF532; HOXA1; TCF7L1; MBD2; PPP1R13L; AR; SMARCC2; IRF4; CREM; NFYC; PRMT2; STAT5A; YEATS2; NPM1; BMI1; SMARCA2; KAT8; SUV39H1; SKI; SAP18; NCOA1; ARID5B; PBXIP1; CEBPD; TBL1X; TRIM16; RYBP; MXI1; TXNIP; ARNTL; TRIM24; NR3C2; RFX7; MED12; THAP11; ZBTB38; HIVEP2; PHOX2B; RUNX3; SP100; MITF; DMTF1; SIAH2; TBX3; TFAP2C; HOXB7; HOXC6; TRIM22; PBX3; CITED2; BASP1; RFX5; HAND1; SOX13; SATB1; ZNF248; NCOA4; E2F2; ZNF329; NLK; ATF7IP; FOXJ3; KAT6B; ECD; ZNF22; ELF1; SSX1; TCF12; NR2F1; SOX4; ZEB1; FOXD1; RSF1; MAGED1; HOXB6; PURA; NUP62; PNRC1; ISL1; FOSB; PTTG1; HMGN3; HTATIP2; TCEA1; NFIB; EED; HMG20B; ZSCAN18; HOXB2; LEF1
Down-regulation	131	FOSL1; TCERG1; DNMT1; HMGA2; MYC; KLF10; ZFP36L1; SUZ12; ZBTB7A; MLXIP; BTAF1; EGR2; ZNF512B; NAB1; TEAD4; TFDP1; PLAGL2; SMAD1; SP3; AHR; WT1; MAFF; NAB2; HMGXB4; TAF11; STAT1; CENPB; ZBTB43; CCNC; VDR; WDR77; NFE2; TRIB3; EGR1; MKL2; HIC2; SMARCB1; XRCC6; NR4A3; BACH1; UBE2L3; RXRA; ZBTB11; MYOG; ZNF232; ZNF711; NFIC; HDAC4; TSC22D2; JUNB; ATF5; EGR4; ZNF544; RBBP8; ILF2; PRRX1; PAWR; ZNF217; ZMYND8; ZNF215; SCAND1; GLI3; ERBB4; HOXD1; ID1; CREG1; HOXD3; C1QBP; EP300; ETV4; ATF2; CERS6; RNF138; CRY1; CTBP1; TFEC; SFPQ; CREB3L1; SSBP3; STAT4; ZNF593; TRIP6; ATN1; JUP; BHLHE40; RCOR1; CNOT2; SOX11; NR2F6; TAL1; HMGA1; SATB2; NR1I2; SREBF1; ETV5; HHEX; ZFPM2; NCOR2; ZNF266; RARG; BCL3; RBFOX2; PBX1; SUB1; TCF7L2; NR0B1; ZEB2; TSC22D1; MECOM; MED17; PDLIM1; MYRF; NR4A1; BCL11B; EGR3; ELF3; SNAI2; MAFB; HIRA; TLE1; SOX9; SHOX2; KLF5; FOXG1; ESR1; APEX1; SPIB; FOS; ETV1; PEG3; INSM1