Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17803 Fostamatinib GSE70138 MCF10A Human 3h 0.04uM EID0022
Types Number Response transcription factors
Up-regulation 16 MAZ; HDAC4; SLC2A4RG; MED1; CEBPB; DDIT3; MAFB; CD3D; SMAD1; TP63; PITX1; FOS; HOXB7; MTF2; SUB1; ELK3
Down-regulation 49 RBPMS; CRK; AEBP1; PUF60; MEN1; PBX3; IRF7; HIVEP2; BHLHE41; ZNF34; NEUROD1; ZNF329; ZNF430; TDP2; BRD4; PRDM2; BANP; POU2AF1; JUN; ZBED2; ELF3; HTATIP2; PLAGL1; ZNF415; ERBB4; NFATC1; SMARCA5; KLF6; KLF9; CTBP2; ZNF93; KLF4; WT1; KDM5D; SOX11; MYCL; ZNF91; ZKSCAN1; NR2F1; SOX9; ZIC1; ZFPM2; INSM1; ZNF423; ST18; ZNF331; DACH1; NR4A2; ID4