Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17801 Fostamatinib GSE70138 MCF10A Human 3h 0.37uM EID0022
Types Number Response transcription factors
Up-regulation 33 BHLHE40; EGR1; BLM; AES; TGIF1; JUNB; RREB1; NPAS2; NCOA4; NUP62; RBPMS; TBX3; JAK2; CREM; ZNF652; MAFB; CUX1; ZNF264; BCL11B; PITX1; BACH2; TOX; NR4A2; NR2F1; FOS; SMAD1; FLNA; ST18; HOXC6; SCAND1; JUP; HHEX; PEG3
Down-regulation 21 ACTL6A; ATF2; PEX2; YEATS4; BRD4; CRY1; HDAC9; RUNX3; AR; KLF5; SNAI2; MECOM; ASCL1; ARID4B; BMI1; SPIB; WT1; ZIC1; POU2AF1; BASP1; IRF8