Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17800 Fostamatinib GSE70138 MCF10A Human 3h 1.11uM EID0022
Types Number Response transcription factors
Up-regulation 56 ZNF302; EGR1; E2F5; SETDB1; IRF7; MECOM; POU5F1B; ST18; HINFP; HMGA1; ARID3A; ERBB4; ZFPM2; LPIN2; ETS1; TRIM24; ZNF232; VPS72; FOXO1; NFE2L3; INSR; NCOA2; ZNF83; PEG3; SALL2; ZNF423; BNC2; CBFA2T2; ZNF573; ACTL6A; CBX4; MYCL; ASCL1; ZNF415; ZNF117; MNDA; SOX17; LOXL2; PBX1; NFAT5; TOX; PBX3; ZNF652; ZFP36L1; ZNF264; ESR1; TP63; TOX3; ZNF91; DACH1; AEBP1; SOX11; NR2F6; INSM1; JUP; MEIS2
Down-regulation 28 NKX3-1; SMAD7; ADNP2; ADRB2; NR1D2; NCOA4; PPARGC1A; PIR; PTTG1; RUNX3; NR2F2; ID2; HOXC10; TRIP6; FOSB; KAT2B; MXI1; HMGB2; KLF4; KLF2; AFF1; SMAD3; KDM5D; SATB1; HOXC6; NR4A2; FOS; IKZF1