Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17799 Fostamatinib GSE70138 MCF10A Human 3h 3.33uM EID0022
Types Number Response transcription factors
Up-regulation 45 MYBL2; EGR1; NFIL3; NFATC3; MAZ; FLNA; TGFB1; POLR2A; SIAH2; JUNB; FOXM1; ID1; CARM1; ID3; NR2F2; NCOR2; FOXO1; ETV4; HTATIP2; PRKDC; TSC22D1; WWTR1; NR4A1; PITX1; CEBPB; HOXC6; ARID1A; GTF3A; SIX2; ATF4; KLF2; NR4A2; ZNF131; EGR3; RBBP4; MSX1; ERBB2; HOXB7; CALR; NFIB; FOS; FOSB; HOXB6; HOXA5; TXNIP
Down-regulation 55 ZHX2; ERBB4; CREM; CAMTA1; TTF2; WWC1; RORA; BAZ2B; FOXF2; ARID5B; ADRB2; ZNF232; ZNF85; ZNF586; MYCL; ZNF512B; SIX3; MKL2; NANOG; AR; NFE2L3; ZNF93; ZNF91; MYT1L; TCF12; NR2F6; SOHLH2; TCF4; CREBL2; ZNF43; CUX2; NFATC4; HDAC9; CRYM; ETS1; SHOX2; TFAP2C; DACH1; TOX; ZBTB20; ELF5; TOX3; BASP1; EMX2; SALL2; ID4; ZNF589; MEIS2; CREB1; VPS72; TRIM29; ZIC1; BCL11A; ZNF331; PEG3