Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17792 Gsk-1059615 GSE70138 MCF10A Human 3h 10uM EID0022
Types Number Response transcription factors
Up-regulation 44 TSC22D3; FOXO3; GATA3; ID2; MBD2; NCOA6; TAF10; SMAD4; BRD8; HTATIP2; RUVBL2; HBP1; MAFB; HOXC6; HMGN3; FOXN3; REPIN1; ARNTL; MXI1; SOX4; PHF20; ASCL1; NFKBIA; TOB1; ITGB3BP; RBM39; ELF1; ARID5B; CEBPB; ZBTB16; HOXA5; SPEN; RBBP4; KLF9; FOXO1; LITAF; RFX5; ATF4; FOXJ3; PIR; HOXC10; PURA; TBL1X; CREG1
Down-regulation 101 FOSL1; HMGA2; MYC; TAF1A; SUZ12; ZNF556; FHL2; PPRC1; TBP; NANOG; EGR1; SRF; EGR4; ETS1; TEAD4; MAFF; ZNF200; EGR2; NKX2-1; KLF10; AR; LIN28A; NFE2L3; ZNF202; OLIG2; NAB2; ZNF557; ADRB2; NR4A1; WT1; EGR3; KAT6B; ZFP36L1; NR4A3; ESR1; HES1; ID1; MYT1; PEG3; BRWD1; SOHLH2; ETS2; ZNF273; ZNF141; PKNOX2; BHLHE40; ZNF334; FOXF1; ZNF43; ZNF516; KLF4; LOXL2; ZNF85; TFAP2C; JUNB; JUN; ZNF117; TCF21; ZNF93; ZEB1; ATF3; TRIB3; ZNF253; NR4A2; TOX3; HDAC9; ST18; ZNF124; CEBPZ; HIC2; ZNF239; ELF3; CRYM; DLX2; SOX11; NKX2-2; OSR2; TGFB1; BASP1; PRRX1; ZNF512B; NEUROD1; HOXB2; HOXA10; NFATC4; SOX9; FOSB; CUX2; ZFPM2; IRF8; ZIC1; IRF6; MYRF; FOS; HHEX; DACH1; SSBP2; PBX1; MEIS2; ZNF331; INSM1