Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17772	Alvocidib	GSE70138	MCF10A	Human	3h	1.11uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	DAXX; ZNF667; TCF3; EPAS1; L3MBTL1; BBX; ZNF224; SNAI1; ZNF665; NR1D2; ZNF91; LIMD1; TCF4; TCF7L1; PAWR; CERS6; SIRT2; PRRX1; CARHSP1; ZNF257; ZIC3; ZNF711; E2F5; MYCN; HOXC11; SHOX; GLI2; MXD4; ZNF423; NEUROG1; MXI1; ZNF177; DLX4; PBRM1; YBX2; ZSCAN18; RING1; HAND1; PRDM12; BCL6; NHLH1; MYT1; AEBP1; LIN28A; SOHLH2; HOXA3; ZNF135; TOX; SHOX2; ZKSCAN4; CDIP1; EN1; TBX1; ZNF835; ZNF606; TCF7; SIX6; FOXO4; PEG3; CREB1; SRY; BARX1; MED12; ETS1; MYBL1; SUPT3H; PRDM2; TWIST1; HOXC4; ZNF415; PAX5; ZNF264; TRPS1; BNC2; LHX3; MXD1; NFATC4; MEIS1; BCL11A; LEF1; ZNF623; KAT2B; NCOA1; ZNF43; FOXF2; PAX6; ZNF239; ZNF611; ZFPM2; ID4; SMARCA1; RBFOX2; LOXL2; CBX4; HMGB3; TOX3; ZBTB20; NFATC1; MAF; ID1; THAP11; TOB1; SALL2; PBX1; PBX3; BACH2; PLAGL1; ERBB4; NEUROD1; DLX5; FOS; ARID5B; ST18; NR5A2; ZMYND8; SOX2; ZIC1; MEF2C; DACH1; VPS72; INSM1; MEIS2; NR2F6
Down-regulation	99	MYC; FOSL1; NFKBIA; TBP; ABL1; CCNA2; FHL2; SUV39H1; TBPL1; HMGXB4; EGR1; ADRB2; ZNF468; FOXO3; RNF111; IFI16; TGIF1; SMAD7; XBP1; EZH2; ATF1; E2F6; CEBPB; MAFG; MED4; CDK7; EGR2; MED6; KAT6A; MED23; ZBTB1; ADNP2; HSF2; BRPF1; GABPB1; TRIM32; SMARCA2; BHLHE40; NFIL3; ZZZ3; CEBPA; HOXA5; SERTAD2; BAZ1A; TSC22D2; AFF1; HOXA1; TBL1XR1; DDX5; KLF6; NRIP1; ZNF267; USP22; NPAT; FOXM1; PSPC1; ILF2; ELF3; ARID4B; PCGF2; ELF1; MGA; CBFB; SOX4; HOXA7; HES1; MED17; ELK3; TSC22D1; SOX9; HOXA10; ZNF217; RNF6; RUNX3; CHD7; TLE1; HOXB7; MED1; NKX2-1; JUND; ETS2; NUP62; NR2F2; EGR3; AHR; CENPF; EED; ZFP36L1; HOXC6; NKX3-1; NFIB; ZFP36L2; APEX1; SMAD3; TRIP6; ZBTB18; FOXJ3; SUB1; ATF3