Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17753	Withaferin-a	GSE70138	MCF10A	Human	24h	10uM	EID0021

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	EGR1; RELB; ATF3; SUPT3H; CBX4; TGFB1I1; IRF9; IRF7; THAP7; MED25; ARID5A; PPARD; JUNB; SPI1; MED15; TBX3; HDAC5; JUN; ZBTB7A; JUP; CDX1; ZNF580; GATA6; GTF2F1; ZSCAN9; TBX21; STAT4; SNAI2; VDR; AES; PKNOX2; FOS; TULP3; CALCOCO1; NR1H4; PIAS4; MTF2; EYA1; MEIS2; BTG1; NR4A1; HDAC9; CERS4; CBX7; ZNF423; ZNF532; TSG101; RORA; IRF6; TRIM24; XBP1; JUND; KAT6B; PBXIP1; ATF4; ZNF536; SIX2; CREB3L1; KLF4; TCF21; IRF4; LMCD1; INSR; GATA2; DDIT3; FOSB; DACH1; GATAD2A; EDF1; HIRA; ZBTB20; CD3D; CDIP1; ZMYND8; KDM5D; SOX3; ST18; CREB3L2; ZHX2; CARHSP1; THAP11; ZIC3; PLAGL1; FOXF1; HIC2; SOX10; FOXF2; FOSL2; MYCL; LITAF; MXI1; BCL11A; TCF7L1; ZBED2; NR4A2; DLX5; HHEX; TOX3; ZNF91; KLF2; CBFA2T3; LIN28A; VPS72; TRIM29; ZNF331; LOXL2; TRIB3; SOX9; ZNF652; NANOG; ARNT2; WT1; AEBP1; POU2AF1
Down-regulation	91	RUVBL1; MYC; PRKDC; CRK; CCNA2; HDAC2; TCERG1; MKL2; HOXA5; RUVBL2; TFDP1; BCLAF1; CNOT1; NRIP1; NR3C1; GTF2I; CENPF; POU4F1; SMAD5; BMI1; SMAD2; ENO1; TRRAP; ASH2L; CEBPZ; RB1; FOXO3; ZNF146; DNAJC2; NFIL3; SMAD1; MTDH; ZBTB11; CBX3; PSIP1; HES1; KAT6A; HDAC1; PMS1; HIPK3; ATF1; ZKSCAN1; CCNC; RBBP4; MED6; NFIB; CLOCK; COPS2; ZBTB38; BIRC2; AHR; BAZ1A; TCF12; PAXBP1; SFPQ; ZMYM2; PBRM1; TFAM; BHLHE40; PURA; CBFB; DEK; CNBP; ZNF148; SP3; ZMYND11; NR1D2; ADRB2; HMGB1; HLTF; RBBP8; SPEN; IFI16; KLF9; STAT6; NAB1; TRIM16; HMGB3; NFKBIA; HMGB2; HOXC6; STAT3; TRIP6; SAP30; ELK3; KLF10; ERG; MECOM; HOXB7; TRIM22; BASP1