Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17751 Mitoxantrone GSE70138 MCF10A Human 24h 0.12uM EID0021
Types Number Response transcription factors
Up-regulation 26 MEF2C; KLF2; ETS2; MAGED1; TRIM22; PBXIP1; ZMYM2; BASP1; RFX5; ZBTB38; IRF7; STAT1; SIAH2; SMARCD3; ELF1; ELK3; RBPMS; FOSL2; TRIM16; ZNF83; TSC22D1; AFF1; FOSB; BHLHE41; TRIM29; NR4A2
Down-regulation 87 CCNA2; SLC2A4RG; DBP; AGO2; PITX1; CCNH; ZEB1; CALR; EN1; TWIST1; HDGF; CARM1; FOXL2; PA2G4; MYBL1; SIX2; TFDP2; FOXM1; MSC; HMGB2; NR5A2; HOXC4; PITX2; ZNF232; CENPF; KLF9; HMGB1; STAT4; RBM14; HOXC10; NR1I2; GATAD2A; ZNF516; ILF2; NR0B2; PRDM10; SAP30; TEAD4; SNAI2; SSBP3; PTTG1; GLI3; TBL1XR1; ARNTL2; HOXB6; ZNF91; VGLL1; SMARCA1; TXNIP; PRRX1; NEUROD1; TCF21; HOXB2; KAT2B; DEK; NR2F6; RNF138; ID1; HHEX; KLF13; TRPS1; MYBL2; LITAF; EHF; CUX2; CD3D; PAX5; SMAD1; BACH1; FOXF2; CHD7; TCF7L1; NR2F1; NFIB; WT1; NFATC4; ARID5B; HMGB3; INSM1; MYRF; ID4; MEIS2; SSBP2; ARNT2; CREB1; SUV39H1; SATB1