Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17747	Mitoxantrone	GSE70138	MCF10A	Human	24h	10uM	EID0021

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	RELB; NCOR2; GATA2; PNRC1; IRF7; MXD4; E2F2; PHF1; PPP1R13L; SMAD2; HIVEP1; MZF1; HDAC6; NR2C1; TSC22D3; FHL2; ZNF222; LPIN2; SREBF2; ID3; TBX3; CBX7; MBD1; PBXIP1; ZNF195; FOXF2; ATF3; KLF12; TFDP2; EZH1; ZNF84; NFKB2; FOXO4; ZNF415; PHOX2A; ZNF268; HBP1; NFIX; WNT4; ZBED1; FOSB; THRA; SP100; LMX1B; CSDC2; CHD3; BCL3; TRIM16; RING1; HDAC5; SMAD6; TBX1; ZSCAN9; KLF6; PRRX2; ZNF529; DLX4; NR0B1; SMAD7; MYCL; ZNF350; TSG101; USF2; TP63; TRIM29; TSC22D1; MYT1; TLE2; JUP; TRIM22; ID2; JUNB; MXI1; CREBL2; CDX1; ZMYM2; HMBOX1; NR4A3; SSBP3; IRF9; HOXB13; FOSL2; ZNF226; TAF10; HOXD1; ARNTL; MDM2; BRD8; ZSCAN18; CDIP1; NEUROD1; TCF7; OLIG2; TOX; RSF1; PDLIM1; RFX5; NKX2-1; KLF13; HTATIP2; NFKBIA; CUX2; MEIS1; MYCN; ASCL1; NCOA2; ZFPM2; ID1; PIR; TRPS1; ELF3; TAL1; STAT1; FLNA; INSM1; FOXF1; KDM5D; NR4A1; MAF; SCAND1; BASP1; SNAI2; STAT3; BHLHE41; TOB1
Down-regulation	78	CCNA2; EZH2; TFDP1; ZNF263; CDK2; DNAJC2; RUVBL2; SAP30; CENPF; FOXM1; RUVBL1; PA2G4; TLE1; TRIM28; BRCA1; TFAM; ARNTL2; BRIP1; CEBPG; HMGB2; PMS1; VGLL4; PSMC3; ILF2; HMGB1; CEBPD; CCDC59; CCNC; ELF5; E2F8; CBFB; BRD7; BLM; MYBL2; HDAC2; SSRP1; CHD7; TXNIP; TEAD4; ZNF593; TAF9; PTTG1; CCNE1; FOXO1; PRKDC; ZNF22; CREB3L2; HES1; GTF2I; HOXC10; CALR; NR2F2; MKL2; RYBP; BAZ1A; WWTR1; CEBPZ; MAFB; KLF9; BCLAF1; ERG; RBBP8; TAF9B; SOX11; RNF138; HOXC6; ING3; NFIB; SMAD1; MNDA; SUV39H1; BACH2; ZNF652; NANOG; TCEA1; HHEX; KLF5; SATB1