Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17722 Torin-1 GSE70138 MCF10A Human 24h 0.12uM EID0021
Types Number Response transcription factors
Up-regulation 66 TBX2; TGFB1I1; CUX1; HBP1; SOX4; TSC22D3; CSDE1; ZNF160; CALCOCO1; HMGA2; RCOR3; ZNF281; FLNA; NAB2; AES; MEIS1; FOXN3; RBFOX2; ZNF358; SNAI2; CHD9; STAT6; HOXB5; ERBB2; TGFB1; ZNF611; LITAF; ELF4; TLE2; PHF20; TAL1; BASP1; TCEA2; ZBTB16; IRF6; CRYM; NEUROD1; MEOX2; HOXD1; BCL11A; HOXB6; ZMYND8; FOXF2; AHR; HMGA1; HLX; NFAT5; FOXD1; FOXO1; TRIM22; ZFP36L2; TXNIP; IFI16; GATA6; HDAC9; NFATC4; EHF; RBPMS; MECOM; ARNT2; ZBED2; HOXB2; CITED2; ZFPM2; SOX9; SOX11
Down-regulation 47 CCNA2; GTF2A2; RBM14; TFAM; TFDP1; MYCBP; CCNC; C1QBP; ETV1; TBPL1; EZH2; RUVBL2; HOXA1; HSF2; PREB; CCDC59; HDAC1; FOXM1; BLM; SFPQ; SUB1; HNRNPD; EED; BAZ1A; SSX1; RBBP8; PUF60; HMGB2; PTTG1; RNF138; XBP1; NFATC1; RYBP; HLTF; MAGED1; SOX10; MYBL2; SAP30; PIR; ISL1; NR0B1; SUV39H1; ESR1; FOS; LEF1; HOXC6; CREB1