Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17718	Torin-1	GSE70138	MCF10A	Human	24h	10uM	EID0021

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	SOX4; TSC22D3; HBP1; FHL2; HDAC6; ZNF76; SRCAP; CALCOCO1; CIR1; PBXIP1; EZH1; FOXO4; HOXB13; PNRC1; EP300; AES; ZNF337; IRF9; HOXD1; CDK7; FOXO3; RELB; SP100; DEAF1; GTF2IRD1; REPIN1; MED12; PHF20; BPTF; SUV39H1; CRYM; ZBTB43; ZNF358; TBX21; HDAC5; ZSCAN18; ZNF160; PPP1R13L; ZNF768; ARID5A; ZNF688; NCOA3; TGFB1I1; TCF25; MED15; TSG101; NR3C2; TGIF1; NCOA2; ATF4; ZNF611; ZNF44; HMGA2; HINFP; DLX4; ZNF506; KLF13; LZTR1; ING4; CBX7; ELF3; MZF1; ELF4; IRF6; ARNTL; BAZ2B; ZNF91; HOXB1; HTATIP2; ATOH1; ZNF33B; ERBB2; CREBL2; ZNF426; MAFG; KLF7; LPIN2; ATN1; IRF7; TLE2; THRA; ZKSCAN1; MYCL; MXI1; CAMTA2; ZNF500; ZBED1; THAP11; JUP; KLF6; KAT2B; STAT6; MAFF; PHIP; BACH1; NFIC; BRD4; TAL1; NPAS2; FOXG1; TCEA2; BCL3; ZNF217; NFIX; BTG1; LMCD1; CTBP2; GATA6; ZNF467; MEOX2; FOXO1; SMAD3; HDAC9; CEBPD; ZBTB16; OLIG2; TCF7; REL; DDX17; ZFP36L1; FOXN3; ZNF117; CITED2; TCF7L1; EYA1; ZNF43; SALL2; ZIC1; ZFP36L2; TRIM22; RXRA; KDM5D; BCL11A; ZNF264; DLX5; TRIB3; ZNF652; HMG20B; EGR2; MYBL1; MAF; KLF5; TBX3; TCEA1; SNAI2; KDM5B; ARNT2
Down-regulation	101	MYCBP; CREG1; PARP1; TFDP1; EGR1; CCNA2; FOSL1; TFAM; RUVBL1; GTF2A2; C1QBP; EZH2; DR1; PPRC1; ENY2; WDHD1; NUP62; ATF6; DNMT1; UBTF; HMGB1; SUB1; RBM14; RBBP8; RUVBL2; RBL1; TBP; CDK2; PSMC3IP; BAZ1A; HOXB7; HOXA5; SMAD5; HDAC2; BRCA1; LZTS1; PA2G4; SREBF1; MYBBP1A; TRIM28; BCLAF1; CEBPZ; ITGB3BP; SNIP1; SSRP1; YWHAB; RNF138; TP53; CBFB; EED; MYBL2; FUBP1; PMS1; HLTF; IRX5; PTTG1; ATF5; ILF2; YEATS4; PEG3; TAF9; BMI1; GATAD2A; MSX1; RBBP7; NR2F1; BIRC2; RAN; HNRNPD; HOXB6; RBBP4; ID3; WWTR1; NFIB; MYCN; SFPQ; WWC1; ZNF22; PBX1; CHD7; STAT3; TAF9B; HMGB2; NFIL3; PITX1; ELF1; ID1; PURA; ESR1; HHEX; LEF1; HMGB3; KLF10; EMX2; NANOG; MEIS1; ZNF331; BASP1; MEIS2; FOS; HOXC6