Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17709 Gsk-2126458 GSE70138 MCF10A Human 24h 0.37uM EID0021
Types Number Response transcription factors
Up-regulation 288 TSC22D3; HBP1; CALCOCO1; FOXO4; SOX4; PNRC1; CREBL2; FOXO3; EZH1; HDAC6; PBXIP1; CREG1; ZBTB16; TFDP2; BTG1; IRF9; SRCAP; ZNF33B; MXI1; ARID4B; ZNF606; EP300; ZSCAN18; ZNF91; WNT4; ZNF358; ARNT; KAT2B; TAF12; ZKSCAN4; TCF25; HOXB13; AES; CBFA2T2; CIR1; TCF15; TBX21; PHF1; CEBPD; ZNF688; HTATIP2; ZNF16; ZSCAN16; HIVEP1; ELF4; SP110; SALL2; ZNF85; FOXJ2; SUPT3H; ING4; SIRT2; ZNF419; CBX7; PHIP; TBX10; APBB1; HDAC5; ZNF430; BAZ2B; TULP3; MAF; ZKSCAN3; ZNF160; ERBB4; ZNF778; HINFP; ARID5A; ZFP36L2; ZBTB43; MITF; ZBTB44; BACH1; ZNF224; MED12; FOXO1; ZNF506; MEF2D; NR3C1; DYRK1B; UBE2B; BCL11A; HNF4G; ZNF350; CBX4; ZNF43; TXNIP; HOXB3; OSR2; ZBED1; HIPK1; ZBTB3; KLF3; SMARCC2; DPF2; ZNF500; FOXN3; ZNF268; ATF7IP; CITED2; GATA6; MZF1; BPTF; ZNF135; ZKSCAN1; IRF7; PFDN5; OLIG2; ZNF117; GBX2; RING1; STAT2; NR1I3; ZNF205; MYCL; TGIF1; ZNF768; ZNF354A; ZNF93; ZBTB20; ZNF671; SPI1; CTBP2; HIF3A; SP100; EVX1; ZFHX2; ZHX2; ARID5B; ZNF219; TCEA2; ZNF623; PIAS1; TRIM22; ZNF611; ZXDC; ZNF362; HOXD13; ZNF217; ERBB2; ZNF175; CSDE1; CERS4; SETDB1; TCF7L1; DLX4; ZNF446; THRA; ZNF14; ZNF254; NFE2L1; SCAI; LMCD1; NR1H4; THRB; MXD4; ZNF264; ARID3A; GRHL2; ZNF112; LZTR1; ZNF189; PRDM2; NR5A1; CUX2; NR4A2; CSDC2; STAT6; ATOH1; ZNF133; SP140L; ZEB1; SOX3; FOXH1; WWP1; ARID1A; ZNF467; BARX2; SSBP3; BAZ2A; CUX1; ZNF44; MED15; ZNF426; NCOA1; ID4; HOXA3; MAZ; JAK2; HOXB1; TRPS1; TLE2; ZNF345; TCF21; TEAD3; TCF7; ZFHX3; PKNOX2; HMBOX1; SRY; CARHSP1; CDK9; TSG101; KLF6; GFI1B; TCF7L2; ATF4; NCOA3; JUND; ZSCAN31; PRDM14; NFIL3; AFF2; RUNX1; ZIC3; AEBP1; ZNF304; RXRA; ELF3; MAFB; HMG20B; KLF9; TGFB1I1; PAWR; DLX5; ZNF665; ZFPM2; JUP; ZNF75D; RORA; RARG; HDAC9; HOXB5; NPAS2; REPIN1; TCF4; BRWD1; FOSL2; MYRF; IRF8; IRF6; NR1H2; ZNF652; SPIB; ZNF12; BACH2; CRYM; MYCN; NCOA2; THAP11; HOXD1; NFATC4; ZNF107; ARNT2; ATF3; HEY1; KLF13; AFF1; AHR; MNDA; TFEC; TRIB3; ST18; TSC22D1; KLF5; KLF4; ZNF83; INSM1; PBX1; NFKBIA; ZNF331; LIN28A; FOSB; KLF2; TLE4; CBFA2T3; KLF11; HIC2; MEOX2; NFE2L3; TCEA1; MEIS1; HOXB2; CREB1; INSR; SSBP2; BASP1; FOS
Down-regulation 85 FOSL1; MYCBP; PARP1; C1QBP; TFDP1; TCERG1; MYC; RUVBL1; EGR1; NUP62; PPRC1; CCNA2; EZH2; DRAP1; WDR77; RBM14; RUVBL2; GTF2A2; RBBP8; TBP; SUB1; TFAM; PITX1; ATF6; HDAC2; SUZ12; SSRP1; RBL1; CHAF1B; TRIM28; YWHAB; ETS1; GABPB1; HSF2; CBFB; BCLAF1; WDHD1; RAN; HOXA7; SMAD5; TP53; PSMC3IP; BAZ1A; HMGB1; PA2G4; HLTF; HES1; TAF1A; RBBP7; TAF9; PRKDC; ILF2; EGR4; RNF138; EED; CTR9; IRX5; ATF5; NPM1; EGR3; RNF4; SMAD7; ORC2; ENO1; URI1; CHD7; XBP1; SMARCA5; ITGB3BP; CEBPZ; GATAD2A; HNRNPD; BRCA1; SFPQ; BATF3; ZBTB18; ESR1; HMGB2; ELK3; LEF1; CALR; PTTG1; MYBL2; SUV39H1; PUF60