Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17708 Gsk-2126458 GSE70138 MCF10A Human 24h 1.11uM EID0021
Types Number Response transcription factors
Up-regulation 224 TSC22D3; HBP1; SOX4; BTG1; FOXO3; FOXO4; CALCOCO1; ZBTB16; PBXIP1; EZH1; PNRC1; PHF1; CREBL2; CREG1; CBFA2T2; CIR1; ZNF688; ZFP36L2; PHF20; CBX7; MXI1; FOXN3; SIRT2; FOXO1; HDAC5; ARNT; CEBPD; TCF25; SRCAP; TXNIP; RXRB; ZNF33B; ING4; ZNF358; UBE2B; TGIF1; SP100; MAF; HTATIP2; IRF9; OSR2; ZNF354A; SETDB1; ZSCAN18; HINFP; BACH1; TSC22D1; CRTC1; SPI1; MITF; NFE2L1; TCF15; PSPC1; JUP; NHLH1; APBB1; MZF1; ARID5A; MYCL; ZNF446; GATA6; EP300; ZNF768; ARID5B; REPIN1; PPP1R13L; ERBB2; SMARCC2; ARID4B; NR2C1; TULP3; RBPJ; NR3C1; TLE2; ZNF217; ZNF506; MED15; PRDM2; TSG101; CARHSP1; TCF7; ZNF184; ZNF93; ZNF606; SUPT3H; ZKSCAN1; ZSCAN16; HMBOX1; HOXD1; DYRK1B; ZMYND8; ZNF500; SMAD4; NFATC1; ZNF771; STAT2; KLF9; TCEB2; GRHL2; LPIN2; ZBTB20; BCL11A; AES; PFDN5; MED12; HIF3A; ATF4; ZNF219; ATOH1; TRIM29; RING1; NCOA2; ZNF623; RORC; SP110; HOXB1; ZNF611; ZFHX3; WNT4; LITAF; IRF6; ZNF85; CSDC2; ZNF160; CDX1; ZNF671; ZNF224; PATZ1; SSBP3; ZBED1; PLAG1; BCL6; MAZ; ZNF91; KLF4; MXD4; TGFB1I1; YBX2; ZNF532; MXD3; BAZ2B; NR3C2; ZNF665; ZNF268; THAP11; ELF3; INSR; JAK2; ZNF44; CDIP1; NCOA3; ZNF444; TSHZ2; BCL10; GTF2IRD1; ZNF467; ATF3; TCEA2; SOX10; ZNF43; HMG20B; KLF7; TEAD3; ZNF264; HOXB13; PCGF3; PIAS4; TAL1; ZHX2; NFIL3; KLF11; TCF7L1; KLF2; CUX1; ZNF652; NPAS2; BRWD1; SOX2; ZNF117; PAWR; ZFPM2; CBFA2T3; DDIT3; TCF7L2; AEBP1; ATN1; ZNF32; ZNF12; TRIM22; RXRA; NR1H2; ZMYM2; ZNF536; TCF4; CITED2; BACH2; VGLL4; SALL2; ARNT2; CERS4; HIC2; FOSB; KLF6; NFATC4; NFE2L3; STAT5B; ZIC1; INSM1; IRF8; NR4A2; MYRF; MEOX2; FOS; TLE1; TBX3; ST18; PBX3; ZNF331; ZNF423; TLE4; TOB1; SOX17; VPS72; E2F2
Down-regulation 96 FOSL1; MYCBP; PARP1; C1QBP; MYC; TFDP1; RUVBL1; CCNA2; TCERG1; PPRC1; EZH2; GTF2A2; DRAP1; SUB1; EGR1; NUP62; BCLAF1; DR1; WDR77; TFAM; SUZ12; RBM14; RUVBL2; WDHD1; DNAJC2; GABPB1; EGR4; PITX1; RBL1; BAZ1A; TRIM28; EGR3; HDAC2; PSMC3IP; HMGB1; BHLHE40; HOXA5; POLR3F; HES1; CBFB; PRKDC; ILF2; ENO1; BRCA1; SFPQ; MYBBP1A; CEBPZ; SMAD7; PA2G4; LZTS1; TAF9; SSRP1; BATF3; IRX5; ZNF593; YWHAB; PMS1; RAN; EED; HNRNPD; NPM1; HLTF; TAF1A; CCNC; URI1; CBX5; GATAD2A; WWC1; ITGB3BP; RBBP7; RBBP4; MYBL2; PUF60; CTR9; HMGB2; PSIP1; XBP1; SAP30; BMI1; JUN; TAF9B; ADRB2; DEK; PTTG1; SPEN; WWTR1; KLF10; SUV39H1; PEG3; ERG; SMARCA2; HOXB6; ESR1; ELK3; SOX9; CREB1