Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17707 Gsk-2126458 GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 208 TSC22D3; HDAC6; FOXO4; SOX4; HBP1; CALCOCO1; FOXO3; CREBL2; PNRC1; PHF1; BTG1; CREG1; PBXIP1; EZH1; ZBTB16; TCF25; ZNF688; CBFA2T2; RELB; EP300; HTATIP2; CEBPD; UBE2B; CIR1; MED12; ING4; CDK7; DPF2; ARID4B; ZMIZ2; CBX7; AES; ZNF358; PFDN5; PSPC1; HDAC5; KDM5D; BAZ2B; FOXJ2; ZBED1; FOXN3; FOXO1; ZSCAN16; ERBB2; ZFHX3; ZNF33B; ZNF506; ATF4; ZSCAN18; PHF20; MAF; ZKSCAN4; OSR2; PHIP; ARID5A; ZNF189; NR3C1; ZMYND8; NCOA4; ZNF606; TXNIP; APBB1; NPAS2; RBPJ; GATA3; ZBTB3; TCEB2; TCF15; AIP; ZZZ3; ZFP36L2; IRF9; ZNF91; MITF; TBX21; RORA; SSBP3; ZFY; TULP3; IRF5; MZF1; NR2C1; TSC22D1; DYRK1B; TGFB1I1; JUP; PRDM2; CUX1; NFE2L1; ZNF3; INSR; ARID5B; ELF4; ZNF160; ZBTB20; SUPT3H; THRA; TLE2; ZNF580; SRCAP; LMCD1; ERBB4; KLF3; NCOA1; HOXB13; ZNF354A; TGIF1; CSDC2; MXI1; ZNF44; HMG20B; ZNF500; TCF7L1; SALL2; FOSB; HIVEP1; HDAC4; REPIN1; LPIN2; ZNF671; NR1H3; ARNTL; ZNF768; SCAI; HMBOX1; ZNF268; NR4A2; SIN3B; NFIL3; NR1H4; SMARCC2; ZMYM2; TRIM24; SP100; ZNF217; ZHX2; ZNF623; ZNF224; STAT4; NKX3-2; CIITA; THRB; TBL1X; CERS4; TULP4; TSG101; ELF3; NCOA3; ZKSCAN1; KAT2B; ZNF611; AFF1; GRHL2; KLF11; ZNF467; BACH1; ATF3; ZNF117; CITED2; SSX1; PAWR; ZNF219; BIRC2; TAL1; HMGN3; IRF6; SOX3; BCL11A; TCF7; CARHSP1; BRD8; SPIB; TRPS1; PQBP1; DDX17; SOX10; FOSL2; MYCL; ZNF43; THAP11; NR5A2; HOXD1; DMTF1; RBPMS; TFEC; PBX1; TRIM29; NFKBIA; MEOX2; AEBP1; VGLL4; MAGED1; AHR; ZNF83; JUND; FOS; ARNT2; ZFPM2; TCF4; DAXX; TRIM22; SNAI2; TOB1; MYRF; MEIS1; ZNF331; TLE1; HOXC6
Down-regulation 109 FOSL1; MYCBP; TFDP1; RUVBL1; MYC; C1QBP; PARP1; TCERG1; WDR77; CCNA2; NUP62; PPRC1; EGR1; WDHD1; EZH2; MYBBP1A; GABPB1; HES1; SUB1; GTF2A2; TBP; RBM14; HOXA7; ZBTB18; TFAM; DRAP1; RUVBL2; NFYA; CCNH; BAZ1A; ETV1; HDAC2; ILF2; PA2G4; DNMT1; SUZ12; WHSC1; BCLAF1; GATAD2A; EED; XRCC6; RBL1; HMGA2; PRKDC; PSMC3IP; TAF1A; PITX1; CBFB; BHLHE40; ZNF143; ATF5; HNRNPD; TAF5; ENO1; TAF9; HMGB1; DNAJC2; MED6; RNF4; ENY2; ZNF146; YWHAB; MSX1; ID1; RBBP8; MYBL2; CAPN15; CHD7; YEATS4; ID3; RAN; PTRF; CCNC; MTDH; SMAD7; SMAD5; SFPQ; BRCA1; TP53; HLTF; PMS1; EGR3; IRX5; CALR; ITGB3BP; CEBPZ; SF1; NR2F1; ADRB2; ZNF22; NR2F6; PRRX1; NPM1; RBBP4; SMAD1; IFI16; HOXB7; XBP1; PTTG1; LOXL2; DACH1; HOXB6; SOX9; LEF1; ELK3; STAT3; ID4; SUV39H1; PUF60