Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17705 Zstk-474 GSE70138 MCF10A Human 24h 0.04uM EID0021
Types Number Response transcription factors
Up-regulation 63 PAX8; BRCA1; BHLHE41; RERE; PNRC1; EGR2; TGIF1; EMX2; TXNIP; NR1H2; HDAC4; HDAC9; ITGB3BP; MAFB; HIPK3; TDP2; TRIM29; EHF; NFE2; NR2F1; ID4; NPAS2; CREB3L2; TFEC; HOXB2; FOXO1; IRF6; CTBP1; MKL2; ZSCAN18; GTF2IRD1; CEBPD; HEY2; WWC1; PBX1; TP53; KLF5; ZBTB38; HOXB7; NFE2L3; FOXN3; NFAT5; SCAND1; TSC22D1; PEG3; SOX17; RREB1; WT1; CRYM; ZFPM2; TCF4; MYCL; FOSL2; ZIC1; MYRF; KLF4; CITED2; ESR1; ZBED2; MECOM; MNDA; BASP1; SATB1
Down-regulation 34 TOX; ZNF281; MYBL1; HCFC2; PIAS1; ALX1; ZNF7; ZNF586; SMAD7; PAX5; MXD4; ETS1; KAT2B; MEIS2; KLF7; IRX5; ZNF44; FOXD1; KLF10; RORA; PITX1; HMBOX1; HMGA1; KDM5D; TWIST1; TLE1; SOX11; TOX3; RUNX3; TOB1; INSM1; NR2F6; CREB1; E2F2