Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17689 Azd-7762 GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 66 TSC22D3; PNRC1; ZNF467; HBP1; ZNF184; ZSCAN16; TCF25; ZNF606; HOXB13; ZNF593; ZNF551; ZBTB20; SALL2; WNT4; IRF7; HOXB5; IRF9; CUX2; RORA; PBXIP1; BNC2; HOXD1; ZNF224; NR4A2; CBX7; MDM2; HTATIP2; TOB1; REPIN1; PIAS4; TCEA2; ERBB4; ZNF331; TGIF1; BCL11A; NR4A1; TRIM22; IRF8; CREM; AES; CITED2; FOXO1; MYCL; MYRF; BTG1; BCL11B; PLAGL1; RFX5; PBX1; TCF21; ZNF91; TCF4; ATF3; ARNT2; TLE4; FOXG1; SOX11; ST18; CREB1; ZNF423; HMG20B; NANOG; PEG3; SOX17; ID1; ESR1
Down-regulation 33 FOSL1; NUP62; CCNA2; NR2F6; FOXC1; RNF14; CBFB; YWHAB; HMGA2; BCLAF1; RBM14; NPM1; IRX5; XBP1; BRD3; RBM39; SMAD3; PHF20; BLM; RBBP7; ADRB2; HMGB2; HNRNPD; EED; SMAD7; EGR3; NFIB; CHD7; FOXD1; SNAI2; PURA; NRIP1; ZEB2