Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17671 Azd-5438 GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 175 TSC22D3; ZKSCAN1; ZNF91; ZNF85; ZNF467; MEOX1; ZNF419; ZNF273; TERF2; ZNF257; ZFP2; ZNF232; BRCA1; ZNF606; MYBL2; ZNF557; ZNF492; TCEA2; L3MBTL1; ZNF426; ERBB4; CIITA; SUPT7L; POU2F3; ZNF423; ZNF415; ZNF665; MYF5; ZNF217; TFEB; KLF4; CCNE1; ZNF43; CEBPZ; ZNF117; ZNF682; NFATC3; ZNF331; ZNF195; DACH1; KLF3; PBX1; ZNF350; ZNF12; ZNF334; PKNOX2; PRDM2; IKZF3; TULP3; NFE2; ZNF264; ZNF33B; TWIST1; ZSCAN18; NCOA3; SOX3; CTBP2; ARL2BP; HBP1; ATOH1; PRRX1; IRF6; CARF; ZNF136; MYRF; HOXB5; TRIM22; ZNF516; HIF3A; ZNF83; ZNF304; ZNF623; PEG3; BHLHE41; ZNF529; ZNF667; ZNF141; FOXO1; VENTX; NPAS2; FLI1; ZNF107; E2F8; CEBPD; OLIG2; CREB5; BARX1; WNT4; ZNF573; ZNF586; BCL6; SOX2; ZNF430; REL; IRF9; RXRA; HLX; ZNF224; NFATC4; NR4A3; CERS4; HOXB6; ZNF611; KLF13; ZNF93; CBFA2T3; KAT2B; SALL2; NFE2L3; MNDA; ATF3; TCF7L2; CUX2; KLF11; AR; SIX3; WT1; ISL1; ZNF589; HTATIP2; ARID5B; TRIB3; TOX3; MAFB; TRIM16; OSR2; PBX3; MYCN; HOXB2; TAL1; BCL11A; MYCL; NANOG; GATA6; SMARCD3; HDAC9; ARNT2; SOX11; IRF8; LIN28A; MEOX2; ZNF652; EMX2; ELF3; MEIS1; RORA; FOXF1; SOX17; ZHX2; BACH2; BNC2; SOX9; TCF4; INSR; KLF10; TBX3; VPS72; EGR2; ZBED2; DLX5; TXNIP; HEY1; TOB1; CREB1; TLE1; TRIM29; TFAP2C; ZFPM2; ASCL1; TLE4; ESR1; AEBP1; SSBP2; MEIS2; MECOM
Down-regulation 68 CCNA2; EGR1; TRIM28; PTTG1; HMGA2; GABPB1; PMF1; SUB1; CENPF; BCLAF1; NRIP1; HOXC6; EZH2; ATF1; TCERG1; BMI1; JARID2; RBM14; YWHAB; POLR2A; MTDH; SMARCC1; ENY2; JUNB; ATF5; MED24; CARHSP1; NPM1; CBFB; PA2G4; CBX3; MAFF; CTNNB1; RBBP7; ADRB2; KDM2A; SFPQ; FOXD1; CALR; HMGB2; BATF3; SMAD5; ENO1; RBBP4; TAF9B; HNRNPD; MXD4; MAGED1; EED; NR1D2; PSIP1; BRD8; NR2F2; HLTF; PITX1; HMGA1; ELK3; MSX1; HMGN3; TRIP6; NFIB; TGFB1; ZBTB38; HOXC10; STAT3; NFIL3; PURA; SUV39H1