Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17638 Celastrol GSE70138 MCF10A Human 24h 0.12uM EID0021
Types Number Response transcription factors
Up-regulation 52 IKZF1; FOXJ3; DBP; TBX21; GATA6; NFE2L1; FOXA2; TP63; HOXB5; EPAS1; HIRA; BHLHE40; CREB3L1; WNT4; TRIM22; SMARCD2; GATAD2A; BACH2; AFF2; ZBTB16; BTG1; HOXB7; DDIT3; MXI1; NR1H4; RUNX3; ID2; TFEC; TCF21; BNC2; FOXO1; IRF8; IRF6; TRIB3; VGLL1; SMAD1; ARNT2; LITAF; CERS4; HOXB6; HHEX; VPS72; IRF4; FOXG1; DLX5; NFE2L3; HOXB2; EHF; PAX5; AEBP1; INSM1; MEIS2
Down-regulation 24 TRPS1; SKI; CCNE1; CRY1; SP110; BAZ1A; ATF5; TEAD1; ZEB1; SIM2; CALR; KLF6; FOXC1; KLF2; HLTF; ZIC1; MED1; PURA; ELK3; DACH1; ID3; ID4; TBX3; ESR1