Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17631 Cgp-60474 GSE70138 MCF10A Human 24h 1.11uM EID0021
Types Number Response transcription factors
Up-regulation 623 EGR1; ERBB4; ZNF816; ZSCAN18; HOXD3; HBP1; ZNF556; ZNF606; SSX3; ZNF667; MXI1; TBX21; ZNF484; NFATC3; ZNF552; SNAI1; ZNF467; TLX1; MECP2; SKI; ATF7; GLI2; ZKSCAN8; SIX6; ZNF544; IKZF2; SUPT3H; TBX6; DCC; ZKSCAN4; IKZF3; ZNF91; HAND2; SOX18; ZNF350; FOXJ1; ZSCAN2; CRX; HOXC8; ESR2; PEG3; ZNF550; HDAC6; SOX17; REL; NEUROD6; RFX3; NR5A2; ZNF589; HOXA10; ZNF134; ZNF264; ZNF154; CEBPE; PHOX2A; PDX1; TLX2; ZNF221; EP300; MEOX1; TUB; PRDM1; SRY; ZNF586; MDM4; ZNF551; HOXD9; ZNF646; PPARD; FOXP3; ZNF682; ZNF580; NFKB2; GLI1; HINFP; CARF; THRB; DLX6; ZNF345; ZNF132; ZNF223; ZNF695; SSX7; PHF1; MYCN; ZNF136; LZTS1; ZNF500; RFX1; HNF4G; SALL2; TWIST1; MED25; ZIC4; DLX5; NPAS1; ZNF174; SCAI; ARID3B; CIITA; NEUROG1; HEYL; NEUROD1; ZNF253; PAX7; FEZF2; ZNF257; SOX2; ZNF267; ZNF419; ETV7; PROP1; POU6F2; ZNF273; ZBTB7B; CD3D; ZNF688; SSX1; HOXA3; SOX3; THRA; KAT2B; LHX3; TAF1; MAML3; CALCOCO1; TCEA2; ZNF208; NAB2; SRCAP; ALX3; NR6A1; ZNF536; ZNF75D; PKNOX2; ZNF274; HNF4A; ZKSCAN3; CDIP1; EHMT2; GRIP1; OVOL2; ZNF768; TBX10; ZNF444; FOXH1; ZBTB32; ING4; TFAP4; ZFHX2; TBX5; ALX4; MYCL; ZBTB44; FOXE3; TBX19; PRDM14; HOXD12; CUX2; SKIL; CREBL2; ZNF814; STAT2; NFATC4; CBX4; ZNF85; ZNF549; ESRRB; NEUROG2; ZXDB; HIF3A; POU2F2; HEY1; HOXA2; ZFP69B; IRF9; TFDP2; POU2F3; MYF5; ZNF362; ZIC3; ZNF749; PRDM9; CREB3L2; HDAC5; NR1I3; KDM5C; ATOH1; ZNF711; ONECUT1; SOX10; ZNF442; MEIS2; SOX5; ZNF222; HOXA6; PBXIP1; NEUROD2; ASCL3; ZNF250; PAX2; TULP1; TBX4; RBPJL; NEUROD4; SPI1; GBX1; ZNF780B; RAX; ZNF493; EYA3; HOXB3; SHOX; LZTR1; MYOG; TSHZ2; AFF2; ZNF671; HOXD1; STAT4; EZH1; MYNN; RING1; NKX6-1; ZSCAN16; ZNF415; HMGXB3; VHL; TONSL; CAMTA2; LITAF; ZNF426; ZNF124; ZNF506; ZNF423; ZNF135; MZF1; ZNF225; ZNF835; ZIM2; TGIF2; ZNF654; PRDM2; ZNF770; HOXB8; ZNF205; NEUROG3; ONECUT2; KLF12; TAF4B; NR0B2; HESX1; L3MBTL1; IRF6; NFE2; CDX4; HNF1B; ZSCAN32; ZNF155; ZNF532; WHSC1L1; ZNF81; ARL2BP; RARG; FOXO4; ARID3A; ZNF224; VENTX; POU4F2; ARHGAP35; NHLH1; ZNF234; TCF4; PHOX2B; HOXD11; ZNF235; IFNB1; SCRT1; PRDM13; ZNF117; KLF13; PAX3; HES2; ZSCAN9; CDX2; E2F5; ZNF195; FOXL1; CHD2; NR1I2; EN2; NOCT; HOXD13; LIN28A; SP4; CCNH; ZNF157; ZNF80; ZNF358; HOXA4; APBB1; SIX5; VSX1; ZNF14; BARX1; ZNF430; POU3F2; ZNF778; ZNF254; NKX2-5; GFI1; EGR2; PAX1; ZNF391; FOXI1; HMX1; HOXB1; TEF; EMX1; E2F4; BNC1; POU3F4; NR1H2; E2F8; ZNF74; TBX1; ZNF471; ID4; ZNF492; TCF3; TFDP3; SOX14; SUPT5H; AR; GBX2; CREM; ATF3; NFAT5; HDAC9; RFXAP; ETV6; MED12; BCL11A; PRDM16; AFF3; POU1F1; SSBP3; HIPK2; ZNF304; ZNF674; NR1H4; NR5A1; LHX6; ZNF557; ETV3; ZBTB3; HMBOX1; PAX4; CRTC1; GSC2; TAF1C; GCM2; MSX1; DLX2; ASH1L; NKX2-2; NRL; ZNF507; THAP9; CBX2; HIVEP1; EPAS1; SOX1; MSX2; EVX1; TULP2; NFIX; BRDT; ZNF141; ZNF43; BRWD1; MAPK8IP1; LMX1B; ZNF287; HEY2; RFX2; AIRE; ZFY; ARRB1; ZFP2; TRAF6; ZNF343; HIC1; SIM1; ZNF79; PPARA; THAP7; TFAP2B; SOHLH2; FOXE1; ARID5B; ZNF10; FOXL2; ZNF214; TGFB1; MED14; ZNF33B; CDX1; ZNF665; POU4F3; NR2E1; HOXC5; UTF1; POU6F1; ZNF268; HAND1; FOXB1; KDM4C; NR0B1; LMCD1; ZNF407; TOX; SALL1; ZNF571; IKZF4; BPTF; ARID5A; LBX1; ZNF140; ZNF701; POU3F3; RSF1; FOXD3; ZNF652; PROX1; GRHL2; ZNF93; ZBED2; TAF6L; GFI1B; FOXF1; DLX4; FOXC2; PLAG1; PITX3; MEIS1; ZNF611; OLIG2; ETV2; ZNF329; MED31; PEX14; KLF15; CIC; DOT1L; TCF21; NFIC; ZNF180; MBD4; ZNF440; KLF8; ZNF771; HLF; PAX6; MXD4; ZFPM2; HOXA11; CRYM; TBR1; ZNF34; TCF15; GCFC2; THAP11; PBX1; GATA3; ESR1; HOXB5; ATN1; ZNF529; VGLL1; GATA1; ZNF675; ST18; ZNF184; ZNF232; HIC2; WNT4; ACTL6B; TRIM24; SP140L; WT1; CITED1; BACH2; ZNF177; BNC2; SNAPC4; PAX8; TFEC; SMAD6; MLLT1; HSF4; TFAP2A; SUMO1; ZBTB48; DBP; SIN3B; PRDM12; ZNF133; CBX7; LYL1; TP73; RORB; NHLH2; CALR; VPS72; FUBP1; FOXA2; ZNF248; PIAS4; NCOA3; ZNF446; TEAD3; CHD3; OVOL1; RXRG; TLX3; MYT1; ZKSCAN1; NR4A3; MAFK; ZXDC; CBFA2T3; HHEX; IRF1; PRDM5; E2F1; ZNF165; RBL2; TULP3; SPIB; ETV5; NFE2L3; SOX21; TSG101; ZNF623; TTF2; SIX3; E4F1; ZSCAN31; GLI3; TFEB; RORC; PBX2; HLX; ZNF219; MAK; ZNF239; AEBP1; SMARCA1; MITF; ZNF44; ESRRG; ZNF573; ERF; SOX11; LEF1; BHLHE41; ZNF211; ZNF107; IKZF1; PEX2; SHOX2; GATA6; NKX3-2; ZNF334; CNOT3; YBX2; ZNF22; JUP; TRPS1; TXNIP; GATA2; SPDEF; NR3C2; ZNF331; TAL1; RXRA; CERS4; MKL2; MECOM; ID3; TBX2; FOS; MEF2C; MYRF; TGFB1I1; POU2AF1; PRRX1; HIRA; OSR2; TLE2; ZIC1; BRD4; AES; PBX3; ARNT2; PSIP1; EMX2; TRIB3; RORA; NR4A1; NANOG; MEOX2; MAFB; NR4A2; ZHX2; ZEB1; INSM1; MAF; E2F2; CREB1; ELF5; SSBP2
Down-regulation 174 USP22; MYC; CCNA2; FOSL1; FHL2; TCERG1; TBP; RBM14; CDK7; NUP62; TRIM28; ARID4B; TBPL1; RAN; UBE2I; DR1; MED6; NCOA6; HDAC2; BCLAF1; CTBP2; CRK; SFPQ; HNRNPD; NPM1; FOXJ3; DNAJC2; SNW1; ZNF146; HSF2; YBX3; AATF; CENPF; ADRB2; ING2; RUVBL2; NRIP1; BAZ1A; ZBTB18; YWHAB; NONO; ADNP; RUNX1; PHF20; PTTG1; CEBPG; ECD; ABL1; ATF1; TRIP6; PA2G4; RNF6; XRCC6; NCOA4; SAP30; SMARCC1; CBX5; SMARCA5; SSRP1; RBBP4; UBP1; KDM2A; SMARCE1; CCDC59; APEX1; MAX; HOXC6; ZBTB1; TRIM32; NFKBIA; BASP1; HOXA5; DDX54; COPS2; TP53; XBP1; VEZF1; PPRC1; CRY1; TCF12; HMGB2; HOXB7; KAT7; PRKDC; PATZ1; NELFB; RBBP7; HCFC2; RREB1; ZFP64; ZBTB24; DDX5; KAT5; MED1; ZBTB11; CEBPZ; CTCF; CTR9; EED; HMGB1; TTF1; ZNF302; MEF2A; CNOT1; HMGB3; NFKB1; HSBP1; RBM39; RNF4; JARID2; MED24; ZBED4; PHF2; HDGF; YBX1; RNF111; BRD3; SMARCA2; BAZ1B; ZNF410; BRCA1; ELK3; TOB1; MBD2; CBX3; ATF4; KLF10; ITGB3BP; PUF60; CNOT6; TAF9; BRD8; ENO1; ELF1; DEK; BCL10; NRBF2; ETS2; MLX; RNF138; HDAC1; BRPF1; ZNF281; TBL1X; NCOR2; FOXM1; PIR; SF1; TBL1XR1; SCAND1; NKX3-1; IRX5; TSC22D2; AFF1; EDF1; PCGF2; MTDH; GTF2IRD1; ILF2; TFCP2; FOXD1; SMAD3; DDX17; NFIL3; TRIM16; SUV39H1; NR2F2; KLF6; HOXC10; BMI1; PITX1; ZBTB38; HLTF; IKBKAP