Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17611 Mk-2206 GSE70138 MCF10A Human 24h 10uM EID0021
Types Number Response transcription factors
Up-regulation 73 TSC22D3; SOX4; EGR1; FOXO4; SREBF2; HBP1; PBXIP1; CALCOCO1; FHL2; IRF7; KLF7; BASP1; EPAS1; ZBED1; HMGA2; MNT; RUNX1; IRF6; BHLHE40; NFE2L1; HTATIP2; CREBL2; EP300; SRCAP; TCEB2; ERBB2; IRF5; ZNF217; SMAD3; CBX7; KLF6; NCOA3; ZNF160; MAFF; FLNA; BTG1; ELF4; KDM5D; TRIM29; ZNF281; CTNNB1; TGFB1I1; JUP; ETS2; KLF2; ATF4; AES; CARHSP1; TFEC; CRYM; TAL1; FOXN3; INSM1; MAF; OSR2; TBX3; IRF9; HOXD1; ZNF91; ATF3; LMCD1; ZNF264; KDM5B; MEIS1; BCL11A; INSR; ZNF652; KLF4; TXNIP; ARNT2; SOX9; PEG3; AEBP1
Down-regulation 74 CCNA2; TFDP1; FOSL1; EZH2; CHAF1B; WDR77; C1QBP; MYCBP; TFAM; GCFC2; RBL1; PA2G4; PDLIM1; WDHD1; BRCA1; TAF1A; RUVBL2; ZNF200; TAF5; HSF2; RBM14; BCLAF1; USP16; TTF1; TP53; ALX1; PPRC1; TRIM28; HOXC10; EED; CCNC; ILF2; SFMBT1; ITGB3BP; SSRP1; MSX1; HMGB1; CEBPZ; HEY2; HMGB2; BMI1; PMS1; SFPQ; MTDH; ANKRD1; CBX5; SMAD1; HLTF; HNRNPD; PAXBP1; RBBP8; CENPF; NUP62; NPM1; FOXM1; RNF138; ZNF22; EYA2; RBBP7; CBFB; TAF9B; MYBL2; FUBP1; LEF1; SALL1; ADRB2; HOXB7; PTTG1; WWTR1; SUV39H1; ID1; HOXC6; BHLHE41; EMX2