Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17610 Palbociclib GSE70138 MCF10A Human 24h 0.04uM EID0021
Types Number Response transcription factors
Up-regulation 22 TCFL5; NR1H2; TRIM29; ETV5; ARID5B; ZNF512B; LITAF; RUNX1; FLNA; HMGA1; IRF7; TXNIP; PQBP1; BHLHE40; AES; TP63; KLF5; SOX9; ATF3; TFAP2C; MYRF; HOXB2
Down-regulation 23 HIF1A; CERS6; CTBP2; RBBP8; ING2; KLF7; TOX; SMAD7; SAP30; GATA6; ETS2; PAWR; ZBTB38; CREB1; HOXC10; MYBL1; MED1; EMX2; WT1; ASCL1; HOXC6; KLF9; DACH1