Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17606 Palbociclib GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 23 GATA3; MXD4; IRF7; CREM; DNAJC1; SP110; RNF141; ESR1; SMARCA4; IRX5; TAF10; NR0B1; ETS2; MAGED1; KLF6; NKX2-2; BASP1; AES; BHLHE40; TOX3; ASCL1; MAF; PEG3
Down-regulation 63 CCNA2; ZNF184; EZH2; GMNN; PIAS1; ILF2; TAF5; ZNF473; WHSC1; HOXA5; HSF2; CENPF; BLM; FOXM1; HMGB1; E2F8; UBE3A; RUVBL2; ZNF22; MYBL1; RAD21; BRIP1; NPAT; CHD4; TAF1A; TTF2; NFIB; PTTG1; APEX1; FUBP1; LEF1; ZNF124; CEBPB; TULP3; ZNF232; PAXBP1; HOXB7; ZNF107; ZBTB18; ZNF211; TAF9B; HMGB2; MYBL2; FOXF2; ZEB1; HMGB3; SAP30; TWIST1; DEK; BCL11A; FOXF1; SOX11; SOX13; MYB; ELF5; MEIS2; MECOM; NFE2L3; HOXB6; KLF10; HLTF; CREB1; SATB1