Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17605 Palbociclib GSE70138 MCF10A Human 24h 10uM EID0021
Types Number Response transcription factors
Up-regulation 414 FOXF2; NFATC3; EP300; HINFP; TBX10; ZNF669; ZFP36L2; ATOH1; LHX3; SSX3; TP63; TBX21; FOXF1; BNC1; NHLH1; ARID5B; NEUROD6; TCF21; CREBL2; ZNF816; TBX5; ZSCAN18; NEUROG1; TFE3; IRF9; GBX1; TCEA2; ETV7; TULP3; PNRC1; CALCOCO1; SUPT3H; IRF8; NR2C2; IFNB1; FOXN1; RBPJL; TULP2; ING4; ZNF586; ESRRB; PRDM1; NR4A1; LHX6; GLI1; TBX4; ARL2BP; ZNF764; JAK2; TBX6; KLF13; TFAP2A; RFX3; SNAPC4; ASCL3; TUB; ZNF154; MECP2; ZNF134; SP140L; NFKB2; FEZF2; ZNF174; ZNF573; NR4A3; HAND2; PRDM14; TULP1; ZNF506; NEUROD2; WNT4; CBFA2T3; PRDM13; ZNF667; NEUROG3; GLI2; ZNF589; HOXB1; SIX5; PBXIP1; ZNF426; POU6F2; DCC; SCAI; PPARD; MEIS2; CDX4; SUPT5H; ZNF257; MEIS1; RORC; ZNF268; ZNF235; ZNF136; ZBTB43; CCNH; HSF4; SRY; ZFP2; CAMTA2; GRIP1; EYA3; HDAC11; POU6F1; ZNF133; DLX5; RFX2; HEYL; THRA; CRTC1; CRX; TBX19; KAT2B; OSR2; ALX3; ESR2; NR6A1; SIRT2; CBX2; FOXJ1; ZSCAN32; SCRT1; NRL; ZBTB7B; ZNF74; HOXA4; POU2F3; EPAS1; HDAC9; HBP1; AR; NR0B2; RING1; HNF4G; SSX7; ZNF140; POU3F3; HMX1; KDM5A; FOXH1; ZNF671; ZNF688; BHLHE41; RARG; ZNF221; NFATC4; SOX2; SRCAP; ZNF665; TFDP2; KLF15; SALL1; PRDM2; PEX14; LMO1; ZNF442; NR5A2; ZNF350; HOXD13; PTRF; ZNF467; SOX5; RFX1; PAX1; ZNF208; HOXA6; FOXL2; BAZ2A; ZNF264; ZNF132; MYF5; PROP1; MAP3K10; ZNF419; IKZF4; APBB1; GFI1B; VHL; CSDE1; TBR1; TCF4; ZNF611; SALL2; INSM1; NR5A1; EMX1; HESX1; PAX7; ZNF512B; BCL11A; ZNF768; TEF; NHLH2; SETDB1; SIX6; TSHZ2; ZFP69B; RAX; ZNF354A; SOX3; ZNF500; ETV2; IKZF3; CHD2; ZNF81; POU2F1; ZNF345; STAT2; ZNF814; GCM1; HOXB13; ZNF93; AFF2; KLF11; ZSCAN2; HNF1B; NEUROD4; ZNF440; ZNF492; IRF6; ZNF654; ACTL6B; CSDC2; PRDM9; CDIP1; ALX4; KDM4C; PRDM12; REL; ZNF471; ZNF423; ZNF225; EZH1; HIVEP1; ZNF606; VENTX; ZNF329; ZNF780B; ZKSCAN8; KDM5C; LZTR1; RXRG; FOXB1; DYRK1B; ZXDC; ZNF695; ZNF223; SOX21; ZIM2; ZNF165; GRHL2; KLF8; HOXA3; CDX1; NEUROD1; GSC2; ZNF415; MAML3; THRB; ZNF180; AIRE; POU2F2; PBX1; NR1H4; TAF6L; HIC1; GATA1; NEUROG2; SOHLH2; TFEC; ATN1; SNAI2; TLX3; TAF1C; ATF7IP; ZNF80; TEAD3; SHOX2; ARID3B; DOT1L; PHIP; KLF1; HIF3A; ZNF33B; SOX17; BNC2; ARID5A; NR1H2; CBX7; ZNF536; TFEB; ERBB4; ZNF835; HOXB5; SP2; PBX3; ZBTB17; POU4F3; VPS72; NFIC; OVOL2; ZNF75D; HDAC5; BRD4; CREB3; ZNF701; MKL1; TGFB1; TP73; CIITA; ZNF224; NFIX; BARX1; ZNF219; FOXI1; TDP2; OVOL1; ZNF682; VGLL1; ZNF652; ZBTB44; DACH1; ZKSCAN1; ZEB1; SOX18; PAX6; EHF; DLX2; FOXA2; PIAS4; ZNF91; HLX; TADA3; ZIC3; ZNF532; ZNF215; ID4; PKNOX2; SSBP3; OLIG2; MYCL; IRF1; TGIF2; NKX2-2; PRRX1; NKX2-1; ZNF141; NFE2L3; HSF1; ZNF304; ZFPM2; ZHX2; AEBP1; ESRRG; EN1; KAT6B; HIPK2; ARNT2; ZNF211; PEG3; HOXD1; HIRA; ZNF117; HMBOX1; SSX1; TSC22D1; LIN28A; MYBL1; ST18; EYA1; TFAP2C; CRYM; POU2AF1; CUX2; CREM; ESR1; BACH1; TRIB3; CNOT3; TCF7L1; RSF1; TAL1; SMARCA1; FOXN3; FOXG1; ZNF43; NR0B1; HIC2; ZNF331; ZIC1; ATF3; SPDEF; HEY2; BACH2; THAP11; TBX2; NANOG; MYRF; HLF; SSBP2; TBX3; ZEB2; PLAGL1; MAF; TOX3; FOS; ID1; MNDA; ZBED2; TLE4; HOXB2; MECOM; MEF2C; IKZF1
Down-regulation 109 CCNA2; EZH2; TRIM28; RBM14; PARP1; CENPF; NUP62; NR2F6; TCERG1; ITGB3BP; TFDP1; FOSL1; SAP30; HOXC6; SSRP1; BRD8; BCLAF1; RUVBL2; CTR9; NPM1; ZBTB18; CBFB; RBBP4; ATF1; PTTG1; PCGF2; TBPL1; HMGB2; CERS6; HMGB1; PITX1; BRCA1; SMARCE1; WHSC1; BAZ1A; CALR; SFPQ; NONO; ZBTB11; DNAJC2; ZBTB1; TAF10; UBE2I; RHOA; DRAP1; HDAC2; RAN; ZNF146; HSF2; MAX; ADNP; PA2G4; PIR; NCOA4; PPRC1; TBL1X; JARID2; AATF; TBL1XR1; PURA; PSMC3IP; TRAK1; PRKDC; BAZ1B; MED1; RBBP7; MAGED1; ENO1; HMGA2; TAF1D; HMGB3; TP53; DEK; AFF1; NFIL3; YWHAB; CBX5; RBM39; HDAC1; NR2F2; BRD3; BLM; HIPK3; BMI1; PBRM1; DNMT3B; TRIM32; HOXB7; HNRNPD; SMAD1; EED; KLF2; EYA2; ELF1; ZMYND8; MBD2; ING3; HOXC10; SIX2; NFIB; ADRB2; VGLL4; HLTF; IRX5; ELK3; SUV39H1; MAFB; MYBL2; PUF60