Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17601	Osi-027	GSE70138	MCF10A	Human	24h	3.33uM	EID0021

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	TBP; TSC22D3; CIZ1; PFDN5; KDM5D; KLF7; CALCOCO1; PPP1R13L; E2F2; HBP1; ESRRA; NCOR2; TGFB1I1; PBXIP1; MED12; NCOA4; CDK7; NRBF2; EGR1; STAT6; DPF2; AIP; MNT; HDAC5; SUPT6H; HMGA2; ZNF415; MED15; SRCAP; SMARCD2; THAP4; TCF12; SP100; ZBTB43; HOXD1; RELA; KLF2; ZBED2; RBPJ; ZNF135; OVOL2; BRDT; ZNF281; SMAD7; TCEB2; RING1; FOXI1; SETDB1; AES; ZNF217; ZNF688; NKX2-1; MECP2; TFCP2L1; ELF4; PRRX2; HMBOX1; ZNF44; ERBB2; SOX4; NR1H3; CAMTA2; TRIM22; FLNA; ZNF91; TSG101; ZNF136; KLF6; TGFB1; RUNX1; SSBP3; ZBTB16; ZNF665; MEOX2; REL; NFIC; FOSL2; NEUROD1; TGIF1; BRD4; MYRF; KLF10; NRIP1; ELF3; PDLIM1; VDR; ZSCAN18; KDM5B; TWIST1; SMARCD3; ZNF264; TRPS1; ZFHX4; ID2; FOSB; ELK3; IRF9; KLF13; ZNF83; FOXD1; HIC2; ELF1; NR4A1; PLAGL1; SATB1; SOX9; TXNIP; ID1; TLE4; TCF4; TLE1; CREB1; FOS
Down-regulation	74	CDK2; CCNA2; EZH2; RUVBL1; DR1; MYCBP; TCERG1; TFDP1; GMNN; PSMC3IP; FOXM1; WDR77; RBL1; FOSL1; DNMT1; TAF5; HMG20B; CTBP2; CENPF; BRCA1; PTTG1; C1QBP; SSX1; PIR; EED; ALX1; ATF5; TRIM27; ITGB3BP; RAN; TTF2; MYBL2; BLM; SALL1; E2F8; NUP62; PHIP; SUB1; HMGB1; TAF9; HOXB7; MTF2; FUBP1; BCLAF1; ILF2; NR2F1; PRKDC; HOXC10; CBX6; TOX3; RREB1; ELF5; IRF4; MYBL1; SATB2; SOX10; RFX5; JUN; SAP30; HHEX; PBX1; SUV39H1; PURA; EHF; BMI1; BHLHE41; NFE2L3; ZIC1; HOXB6; HLTF; PBX3; PEG3; HOXC6; EMX2