Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17597 Pd-0325901 GSE70138 MCF10A Human 24h 0.37uM EID0021
Types Number Response transcription factors
Up-regulation 260 TSC22D3; CREBL2; BTG1; ZNF91; HBP1; CALCOCO1; ATF3; REL; RING1; ZNF415; PBXIP1; MXI1; IRF9; TRIM22; ZKSCAN4; ZNF430; MEIS1; CERS6; GATA3; TFCP2L1; TULP3; PNRC1; ZNF629; TFEC; GLI1; FOXO4; FOXO3; ZBTB16; ZSCAN32; IFNB1; ZNF816; KLF11; ZNF573; ZNF606; ZNF768; ZNF3; ZNF688; ZBED1; SIX5; IRF6; TSHZ2; ZNF264; TAF5L; HIF3A; ZNF268; THAP10; OVOL2; ZNF467; PRDM14; ZKSCAN1; MECP2; NFATC3; ZBTB3; SUPT7L; TRPS1; ZBTB43; GATA6; SOX4; PRDM2; HINFP; NEUROG1; ZNF358; HDAC5; DYRK1B; ZSCAN2; ZNF771; ASCL3; ZNF131; IRF1; E2F6; SPI1; SRCAP; TGIF1; TGS1; ZNF195; CSDE1; ZNF14; HDAC9; NR5A1; ZNF224; CEBPD; ZNF500; MZF1; CIR1; PEG3; NCOA2; BRD2; PROP1; BARX1; LITAF; NFIX; ZNF552; BCL3; DBP; ZNF354A; EP300; PBX1; ZNF140; PDLIM1; ING4; MNDA; LHX3; ZNF331; SNAI2; ZNF136; NFATC4; ZNF257; ELF4; ZBTB44; HMBOX1; SP110; CHD3; ZNF12; HES1; ZNF304; AES; TFAP2A; ELF3; ZNF44; PEX14; ZNF205; THRA; MED12; ZSCAN9; CSDC2; ZNF589; SOX12; ID3; ZNF667; ZFP36L2; SAP18; CDIP1; ZNF112; MKL2; REPIN1; ZNF223; KDM4C; ZNF85; ZMYM2; NFIC; HOXB1; HESX1; ZNF165; ZNF586; FOXN3; CARF; MED13; ERF; ZNF512B; ZNF835; GATA1; SMARCC2; KLF7; EMX1; PHF20; TOX3; SMAD1; OSR2; TCEA2; NCOA3; EHF; SMARCA1; ZNF239; ZNF671; MEIS2; ZNF665; ZNF701; CHD2; IRF7; ZNF345; FOXF1; ARL2BP; TEAD3; THRB; ZNF350; GLI2; ZNF43; MYCL; SALL2; ZNF93; CBX7; YBX2; ESR1; BCL11A; SOX18; ZNF652; SOX3; RNF6; ZNF117; KLF13; MAF; DLX5; WNT4; ZSCAN18; CD3D; ZNF124; AR; SOX2; CUX1; ZBTB1; CERS4; ARID5B; JUP; ERBB4; VGLL1; CREM; CBFA2T3; PHIP; BCL6; TLE2; SPIB; INSR; ZNF611; TBX3; TCF7L2; DLX2; TCF21; ATN1; NFE2L3; NR1H3; NEUROD1; ZMYND8; PPARGC1A; RSF1; KLF9; SCAND1; FOXO1; NFAT5; FOXC1; TOB1; HOXD1; VPS72; ZNF423; ARNT2; NFKBIA; WT1; TLE1; SIX3; JUND; RORA; ELF5; TRIM29; MEOX2; ZHX2; MYRF; TCF4; SOX17; MECOM; NANOG; TXNIP; ID4; DACH1; BASP1; SSBP2; ZBED2; SOX9; INSM1; ID1; MEF2C; IKZF1
Down-regulation 95 FOSL1; CCNA2; EGR1; HMGA2; EZH2; PSMC3IP; TFDP1; BRCA1; TRIM28; HSF2; TCERG1; PARP1; EGR3; PTTG1; ETV1; RBM14; NUP62; RUVBL1; FHL2; AATF; CENPF; GABPB1; WDHD1; WHSC1; DRAP1; HNRNPD; RAN; HMGB2; BATF3; RBL1; FOXM1; SMARCA4; NELFB; TRRAP; PA2G4; ENO1; NOC2L; RUVBL2; PRKDC; YWHAB; PPRC1; ETV4; HSBP1; AGO2; TAF1A; BCLAF1; BAZ1A; MEF2A; ILF2; SSRP1; BMI1; HDAC1; SMARCE1; NR2F2; SMARCA5; NPM1; CRY1; PUF60; C1QBP; CARM1; KMT2A; BAZ1B; BRIP1; MLX; TFAM; HMGA1; PITX1; ZNF692; CHD7; PSIP1; SFPQ; CBFB; UBE2I; EED; GATA4; HOXB7; SUV39H1; CALR; RBBP4; ZEB2; HOXC6; TSC22D2; CARHSP1; TBL1XR1; HMGB1; MYBL2; MSX1; HLTF; PURA; ZEB1; DEK; TRIP6; MED1; EGR2; STAT5B