Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17583 Saracatinib GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 84 ZNF586; GATA2; TSC22D3; TCFL5; ZSCAN18; THAP11; HOXC10; TAF5; KAT7; NR3C2; ZNF552; TXNIP; ZNF468; TAF7; ZFP64; MYB; ZNF443; EYA2; ZNF587; ZNF580; ZEB2; POU4F1; TOX; BHLHE41; PIR; FOXO4; TERF2; COPS5; RNF14; ZNF415; FOXJ3; RLF; HDAC4; LEF1; NCOA4; RBM39; ZNF430; PPARGC1A; CEBPA; HOXC6; SMAD7; RCOR1; SSRP1; TRIM16; NPM1; TP53; BRD3; SATB1; MYT1; BCLAF1; REPIN1; DDX5; CBFB; BRD8; PITX1; OLIG2; SMAD2; TCF7; SAP30; ZBTB38; BLM; RBBP7; KLF9; SMAD3; TCEA1; NR0B1; MXI1; ZNF264; NFIL3; BBX; AFF1; IRX5; HOXB7; EHF; INSR; IRF4; AR; TOB1; TBX3; STAT3; TRIM29; ESR1; PEG3; BASP1
Down-regulation 56 NR4A1; TCF25; STAT6; ELF4; CTBP2; CSDE1; TULP3; ZZZ3; CAMTA1; IRF7; TGFB1I1; MEIS2; RBPJ; NAB2; TRIP6; PLAGL1; PAWR; SMARCB1; ARNT2; TCF21; HMBOX1; PAX6; HIC2; SNAI2; FLNA; ZFP36L1; FOXM1; STAT4; HLX; MYRF; OSR2; CARHSP1; ID3; NFATC4; TCF7L1; HLF; KLF6; HTATIP2; LMCD1; TGFB1; INSM1; TBL1X; TRIB3; EGR3; CUX2; KLF11; SOX9; HHEX; TSC22D2; CREB3L2; ELF5; CREB1; NR4A2; WT1; PBX3; TLE4