Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17571 Fostamatinib GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 35 FOXO3; EGR1; IRF8; HBP1; PNRC1; BCL3; IRF7; PBX2; IFI16; ZNF467; BAZ1A; TRIP6; BTG1; HTATIP2; ARID1A; SNAI2; TP63; CARHSP1; TGIF1; IRF9; VDR; ID1; HLX; ZHX2; TCF4; TCF21; POU2AF1; ZNF264; KDM5D; BCL11A; RFX5; ID4; ZFP36L1; SOX9; MEIS2
Down-regulation 10 ADRB2; DNAJC2; ZNF443; BRIP1; ZBTB18; BMI1; SAP30; STAT1; HMGB2; ATF3