Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17570 Fostamatinib GSE70138 MCF10A Human 24h 10uM EID0021
Types Number Response transcription factors
Up-regulation 55 NR3C1; EGR1; KDM5A; SSBP2; TULP3; ZBTB20; SOX4; ZMIZ1; NCOA3; KLF6; CNOT2; BTG1; CHD9; ZBTB44; MEIS1; MTF2; NFAT5; HLF; ETS2; ZBTB38; ZNF611; ZNF623; ZBED2; ZNF160; INSM1; ZMYND8; ZNF665; JUNB; ATF3; PBXIP1; PITX1; ZNF331; NFIC; HMBOX1; NEUROD1; ZNF43; ID1; TCF7; IRF9; KDM5D; JUND; ZNF91; MEOX2; CREB3L2; KLF10; BASP1; NR4A2; NANOG; TXNIP; WT1; PBX3; ID4; FOS; CREB1; SATB1
Down-regulation 31 HDAC1; ADRB2; C1QBP; ADNP2; ZBTB18; FOXC1; CCNC; CREB3L1; DLX2; MYCL; MAFB; ATF5; RBBP7; TP53; MYCN; HNRNPD; PDLIM1; NRIP1; LEF1; MYB; SOHLH2; HMGB2; ZIC1; ELF5; TWIST1; DLX5; TOB1; HOXC6; MNDA; AEBP1; SUV39H1