Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17566 Gsk-1059615 GSE70138 MCF10A Human 24h 1.11uM EID0021
Types Number Response transcription factors
Up-regulation 43 HDAC6; TSC22D3; CREBL2; GLI2; SOX4; HBP1; CALCOCO1; PBXIP1; PNRC1; TCF25; MZF1; PCGF3; NR1H2; TCEA2; ZBED1; MECP2; NCOA3; ZNF33B; ZNF544; SP110; LPIN2; TP53; CBX7; ZMYND8; ZNF12; ZSCAN18; FOXN3; ZBTB16; FOXO1; TULP3; HOXD1; TRIM22; SALL2; PSIP1; HTATIP2; HLF; IRF9; AHR; AEBP1; EHF; ELF3; TRIM29; CREB1
Down-regulation 38 FOSL1; DRAP1; PSMC3IP; CHD7; HMG20B; RBL1; CCNA2; ATF5; YWHAB; SUB1; CEBPG; AGO2; CRY1; EZH2; SATB2; ETS1; LEF1; SMAD5; URI1; BIRC2; GATAD2A; CREB3L1; PITX1; MTDH; SALL1; SAP30; IRX5; ZBTB18; MYB; HHEX; MYBL2; PIR; HLTF; SUV39H1; ESR1; MNAT1; ID4; SATB1