Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17564 Gsk-1059615 GSE70138 MCF10A Human 24h 10uM EID0021
Types Number Response transcription factors
Up-regulation 355 TSC22D3; HDAC6; HBP1; FOXO4; PNRC1; SOX4; KDM5D; CALCOCO1; FOXO3; EZH1; PHF1; HDAC5; ZNF623; ARNT; ZNF688; HINFP; CBX7; ZNF76; PRDM2; ZBTB3; CBFA2T2; TULP3; BTG1; FOXN3; HOXD1; TFDP2; ZNF606; NCOA2; PBXIP1; ZNF184; DYRK1B; SIRT2; CIR1; ZKSCAN4; ZNF34; ZBTB16; OSR2; ERBB4; ZSCAN16; CBX4; MXI1; DBP; BAZ2A; RXRB; ZNF506; SETDB1; ZSCAN18; MZF1; CREBL2; GRHL2; TCF15; MLXIPL; HOXC4; ZNF768; IRF9; ZNF358; ST18; MYRF; KAT8; GATA3; TCEA2; RING1; SAFB; ZNF500; HSF4; KLF11; CARF; SPI1; PPP1R13L; FOXJ1; ZNF74; THRA; GLI2; TBX4; ZNF177; ZBTB48; ARID4B; KAT2B; ZNF174; TRIP11; ZNF354A; NR3C1; ZNF225; ZFY; CEBPD; NHLH1; RBPJ; ZNF132; ZNF175; ZNF224; ZNF345; ZNF350; ZFP2; HOXD3; ELK4; ZNF33B; SRCAP; ZHX2; ING4; ZNF254; DPF2; ZNF135; ZNF117; AIP; MYCL; TFEB; NR1I3; SCAI; L3MBTL1; MEF2A; APBB1; HMX1; ZMIZ2; JAK2; PIAS4; TLE2; HESX1; FEZF2; CAMTA2; ZNF257; HLX; ETV2; PATZ1; ZNF536; PPARA; MECP2; TBX5; INSR; ZNF492; ZNF467; MYF5; ZNF362; CRYM; ZNF217; ZMIZ1; TRPS1; ALX3; NFATC3; ZNF112; MEF2D; ZNF85; SHOX2; SKI; PSPC1; ZNF444; TXNIP; BCL11A; TERF1; TULP4; CERS4; HDAC9; TCF25; ZNF304; SUPT3H; TBX19; ZNF91; NR2C1; SOX2; KLF9; PIAS1; ZKSCAN8; HIC1; ZNF264; CIITA; HDAC4; PHF20; NCOA3; SMARCC2; RSF1; BPTF; MNDA; HIPK1; AEBP1; NHLH2; LZTR1; ZNF214; BRWD1; MKL1; TULP1; POU6F2; ZNF423; ZNF580; HIF3A; NFATC4; RBL2; EP300; ATF3; PCGF3; NEUROD1; MDM4; ZNF415; MXD3; PAX6; ZNF136; TEAD3; TBX1; ZNF671; SMAD6; ATOH1; THRB; ZNF529; CDK9; CIC; ZNF667; HOXD13; ZNF573; CUX2; ZNF133; ARID5A; SIN3B; ZNF75D; TP73; FOXH1; SOHLH2; LIN28A; SOX3; IRF8; ZNF219; SALL2; SPIB; TRIM22; POU1F1; ATF7IP; TCF7L2; YBX2; SCRT1; HSF1; ZNF232; ZNF675; ZNF682; PLAG1; CEBPE; DLX4; ZNF165; ZNF711; TCF7L1; KDM4C; ATF4; NFKB2; NFATC1; TRIM24; ZIC3; HIVEP1; JUP; CBFA2T3; NR1H4; TCF21; ZBTB44; NEUROG2; THAP10; ZNF205; KLF13; ZNF141; SOX12; ZNF154; ZFP36L2; POU5F1B; SRY; GFI1; DDIT3; HOXB13; ZBTB20; CSDC2; SOX18; RORC; PHIP; VENTX; IRF7; ZNF107; ZNF83; CXXC1; ELF5; ZIC1; RERE; EMX2; CUX1; NFIX; BAZ2B; HTATIP2; GATA6; BACH1; PRDM14; E2F8; NR2F1; SSBP3; INSM1; ZNF93; TFEC; CDIP1; IRF6; ELF4; SOX13; ZNF665; HIRA; TSHZ2; EN1; HMG20B; BCL6; ZBTB17; MYBL1; TSG101; NR1H2; PEX14; MEIS2; EHF; ZNF211; LMCD1; ERBB2; SOX17; BHLHE41; ARNT2; NR1D2; ZNF589; HMBOX1; ZFPM2; ZMYM2; RXRA; CITED2; PAX5; BRD4; TCF4; JUND; NR5A2; TSC22D1; VGLL1; BACH2; FOXO1; NR1H3; VPS72; CNOT3; PBX1; ARID5B; AES; FOS; SIX3; MAFB; ELF3; SNAI2; ZEB2; FOXG1; WT1; PBX3; DLX5; TRIB3; ZNF652; TOB1; ZNF331; FOSB; TLE1; TBX3; SSBP2; MEF2C; TFAP2C; POU2AF1; E2F2
Down-regulation 105 FOSL1; MYCBP; C1QBP; RUVBL1; GTF2A2; TFDP1; TCERG1; HMGA2; DRAP1; YWHAB; WDR77; PARP1; BCLAF1; MYC; DNAJC2; EZH2; RAN; HDAC2; SUB1; NRIP1; FHL2; SFPQ; PCBD1; EGR3; GABPB1; RBM14; NPM1; TBP; CCNC; BAZ1A; CBFB; EDF1; NUP62; PPRC1; CCNA2; PA2G4; ENO1; TRIM28; HMGB1; ADRB2; ALX1; RUVBL2; MED6; CEBPZ; PRKDC; RBBP7; HES1; ADNP; BRCA1; MYBBP1A; TRIM32; RNF4; HSBP1; NEDD8; PSMC3IP; PITX1; SMARCA5; ETS2; ITGB3BP; ECD; TFAM; ELK3; ENY2; ING2; STAT1; CHD7; LEF1; RBBP4; BHLHE40; IRX5; TSC22D2; RREB1; PTRF; HNRNPD; ZBTB18; CTR9; GATAD2A; ARNTL2; MYBL2; HOXB7; MTDH; EED; MSX1; RUNX3; NFKB1; MNAT1; ZBTB38; ATF5; CHD1; SMAD3; MED1; FLNA; NFIB; ID3; KLF10; NR2F2; BASP1; PURA; WWTR1; HMGB2; ID1; HLTF; IKBKAP; SUV39H1; PUF60