Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17559 Jw-7-24-1 GSE70138 MCF10A Human 24h 3.33uM EID0021
Types Number Response transcription factors
Up-regulation 55 TBX2; FOXO3; CREBL2; ZNF688; ZFHX3; ZNF467; MNT; TSC22D3; HBP1; SOX4; ZNF589; SOX2; IRF8; TULP3; CUX1; BCL3; ZNF768; NAB2; JUP; BNC2; PAX8; GLI2; SMARCC2; IRF9; AES; RERE; NR4A1; MYCN; ERBB2; CBX7; BRD4; FOSB; TCF21; HOXD1; KLF6; EYA1; ZNF91; TCF4; MEOX2; HEY1; CBFA2T3; SCAND1; INSM1; FLI1; KDM5D; CREB3L2; FOXG1; IFI16; FOS; WT1; EMX2; SOX11; ZNF331; BASP1; CREB1
Down-regulation 42 CCNA2; MYCBP; NUP62; SUB1; TLE1; RNF4; BCLAF1; HOXA1; CDC5L; RHOA; HMGB1; COPS5; BMI1; ENY2; TFAM; ITGB3BP; CCNC; FUBP1; FOXC1; ZNF200; RBBP4; NFIB; ATF5; SAP30; CTNNB1; BHLHE40; CBFB; STAT3; CHD1; TOB1; ADRB2; NFIL3; IRX5; EYA2; HMGB2; ZBTB38; HOXB7; PIR; SUV39H1; HLTF; MYBL2; ATF3