Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17545 Alvocidib GSE70138 MCF10A Human 24h 0.04uM EID0021
Types Number Response transcription factors
Up-regulation 245 TSC22D3; ZNF91; MEOX1; KLF13; WNT4; HBP1; KLF3; BTG1; IRF9; ZNF93; ZKSCAN1; OSR2; IKZF1; ZNF85; PAX2; FOXO3; ZFP36L2; ZNF257; TLX1; ZNF43; ZNF669; SIX3; PKNOX2; ZNF354A; ZNF419; ZNF688; ZNF33B; BRD4; ZNF3; RARA; CDX1; ZNF232; POU2F1; SP100; ING4; PNRC1; TCEA2; IRF5; MDFI; ZNF264; GLI2; BCL11A; ZNF423; ZNF174; TCF21; NR5A1; LHX1; IRF8; PHF20; FOXN3; EZH1; NFATC3; KAT8; MYCL; CUX1; ZNF248; GBX2; TERF2; E2F5; ZNF358; CARHSP1; CEBPD; SP110; TBX21; MBD1; ERBB4; ZSCAN32; HOXB1; HOXD1; KAT2B; TULP3; HNF1B; MEIS1; CDIP1; ZNF611; PROP1; ZNF136; BACH2; ZNF253; MYRF; ZNF415; ZNF665; FOXJ3; SP140L; ZNF195; MAPK8IP1; SPI1; CREBL2; PRDM12; MNT; VENTX; LHX3; E4F1; ZNF506; POU2F2; RORA; PRDM2; SRCAP; ZNF268; MKL2; CREB3L1; TXNIP; PEX14; GON4L; MED12; CSDC2; GATA6; NFATC1; TULP1; ASCL3; TGIF2; ZNF529; CCNE1; ZNF606; IKZF3; ZNF273; SNAI2; KDM5D; SIN3B; PEX2; CHD8; ZNF141; ZNF623; TEF; TCF7L1; ZNF430; FOXH1; HIF3A; ZNF350; KLF15; IRF7; ZSCAN31; KLF7; ZNF331; ZNF219; ZNF12; ZNF500; TP63; CUX2; IRF6; EMX1; ZNF117; HMBOX1; LEF1; NCOA2; MYT1; ZHX2; NCOR2; DLX4; SRY; ZNF224; PBXIP1; BNC2; ZNF701; TCF7; SERTAD2; SOX17; RXRA; IL16; ZNF573; TP73; DACH1; SOX21; KLF11; ZNF22; KLF4; ZNF266; RYBP; ZNF160; TCF7L2; SIX2; IFI16; PAX8; ZNF768; YBX2; PRRX1; ZIC1; PHIP; MEOX2; SOX3; ZKSCAN7; SMARCC2; BCL6; RARG; HIRA; CBFA2T3; CBX7; FOXG1; SSX1; ZNF589; MECOM; SSBP3; ZSCAN18; SOX2; WT1; PAX5; HTATIP2; VGLL1; MYBL1; HLX; CRYM; ARID5B; STAT4; SALL2; CERS4; HIC2; NR1H2; ZNF512B; FOXO1; TRIB3; HDAC9; TRIM16; TCF4; NFATC4; INSR; ARNT2; VPS72; ZNF83; ZBTB16; ZNF652; ASCL1; MNDA; RUNX3; SPEN; TLE1; SPDEF; SCAND1; CREB1; TRIM22; PEG3; TRIM29; TLE4; FOS; PBX3; MEIS2; CREB3L2; FOSB; AEBP1; HOXB2; SOX11; POU2AF1; ZFPM2; KLF5; SOX9; TFAP2C
Down-regulation 98 CREG1; CCNA2; EZH2; EGR1; GTF2A2; TFDP1; XRCC6; HMG20B; ATF1; BAZ1A; ZBTB18; SUB1; EDF1; HDAC2; RBM14; DR1; ATF5; BCLAF1; TCERG1; HDAC1; BMI1; RUVBL2; CALR; C1QBP; CBFB; CDK2; RBBP4; MAFF; NEDD8; PA2G4; BRCA1; TOPORS; PSMC3IP; SMAD5; HOXA1; ATF4; ITGB3BP; EED; HOXC10; HOXB7; HNRNPD; RNF138; TEAD1; HOXC6; NPM1; NUP62; JUNB; NFIB; RBPMS; C1D; PTTG1; EGR3; HOXA5; DNMT3B; DDX5; TAF1D; TMF1; CBX3; YWHAB; PRKDC; HIPK3; CBX5; TAF9B; HMGB1; SFPQ; ING2; BRIP1; JARID2; HSBP1; PITX1; SF1; RBBP7; NR1H3; CCDC59; HMGA2; CITED1; ZNF281; CTNNB1; NR2F1; BLM; SAP30; CITED2; SMARCA2; TGFB1; MTDH; TBL1XR1; TRIP6; STAT5B; HLTF; IRX5; BHLHE40; WWTR1; MYBL2; NFIL3; HMGB2; IKBKAP; SUV39H1; MNAT1