Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17537 Geldanamycin GSE70138 MCF10A Human 24h 0.37uM EID0020
Types Number Response transcription factors
Up-regulation 231 FOXO4; TSC22D3; PDLIM1; CALCOCO1; PNRC1; CEBPA; CREBL2; ZKSCAN4; HOXA5; BPTF; RXRB; PBXIP1; TRPS1; ZNF117; ZNF665; ARID4B; ZMYM2; TCF15; PPARG; HOXB3; ZNF135; AES; ZNF286A; ARHGAP35; GCM1; SIM1; ZNF219; ZNF536; TRIM22; HDAC5; OSR2; ZNF91; SIRT2; NCOA2; HNF4G; ERBB2; ZNF446; AFF2; ZNF175; HBP1; TRIM29; HOXD1; ATF1; TBX5; PPARA; APBB1; ELF4; TEAD3; TFAP2C; NFAT5; EZH1; JUP; SOX4; EBF2; TP63; TCEA2; ZKSCAN1; SIX6; BAZ2B; HOXA3; HOXA4; HOXD3; TCF25; NR1H3; SUPT7L; HDAC7; ING4; SETDB1; RNF111; ZSCAN18; EPAS1; SMAD6; ZFHX3; ZHX2; MZF1; DLX4; ST18; ERBB4; ZSCAN31; TCF7L2; NFE2L1; BARX1; THRA; HINFP; TSG101; CHD9; ZNF223; SOX18; ZNF44; TSHZ2; KDM4A; ZNF384; TCF12; IRF9; MYCL; STAT5A; PFDN5; PBX1; LITAF; ZNF358; ZNF606; SPI1; DDIT3; CBFA2T3; ZNF224; SRCAP; ZNF160; E2F8; ELF5; PRDM10; SMARCA1; SMAD4; DLX5; CRYM; IRF6; ZMIZ1; ZNF544; RARG; ZNF587; RXRA; SIX3; TCF7; VPS72; ZNF264; DBP; ZNF611; MYCN; HOXB2; MED12; ZNF24; TLE2; TP53; ZNF33B; KAT2B; CDYL; CBX7; MEOX1; EMX2; NFATC1; ZNF83; AR; ZNF444; INSR; GRHL2; PHIP; TFAP2A; MKL2; TERF1; CUX1; ZNF112; TCF7L1; SOX13; ID4; MEOX2; STAT6; ZNF304; HIC2; TFEC; PHF1; NFATC4; TBX3; ZNF711; BCL11A; RSF1; ZNF148; PEG3; ZNF415; OVOL2; SREBF1; HMBOX1; MED23; SMAD2; PCGF2; EHF; TFDP2; SALL2; NAB1; NCOA1; BRD2; ZNF331; ZNF430; MECOM; TXNIP; MITF; ZNF350; MED14; KAT6B; BBX; PAX6; CREB3L2; BTG1; ARNT2; TRIB3; ELF1; KLF13; TOX3; ZNF165; HEY1; ZNF721; PIR; ZNF423; ZNF652; KLF5; FOXN3; SMARCD3; HOXB5; TGIF1; MAF; SOX10; TCF4; JUND; TLE4; TSC22D1; NR3C1; MYRF; KDM5C; BCL6; KDM5B; NKX2-2; KLF11; ELF3; BRD4; BASP1; PLAGL1; HOXB6; MEIS2; POU2AF1; HMG20B; ARID5B; GATA3; SSBP2
Down-regulation 114 FOSL1; HMGA2; TFDP1; ADRB2; CCNA2; RUVBL1; MYC; C1QBP; NFKBIA; TCERG1; EGR1; EZH2; SUV39H1; PARP1; ETV1; RBM14; CDK2; TBP; CHAF1B; PSMC3IP; MYBBP1A; NUP62; PPRC1; WDR77; MYBL2; HNRNPD; NFKBIB; BRCA1; CHD7; DRAP1; SUB1; DNMT1; CAPN15; NFIL3; NOC2L; RNF4; TAF1A; KMT5A; SMARCA4; TRIM32; TAF4B; UBE2I; NELFB; UBP1; CARM1; PA2G4; RUVBL2; DNAJC2; CBFB; RBL1; ZNF200; RNF138; TCFL5; EGR3; HSF2; TEAD4; CTBP1; CEBPZ; YWHAB; PTTG1; SSRP1; BIRC2; RAN; BAZ1B; KLF6; TAF9; ZNF23; ZBTB18; TRRAP; BCLAF1; ING2; CRY1; GATAD2A; ELK3; FOXM1; NR2F1; DR1; KLF7; ETS1; XRCC6; HMGB2; WHSC1; CEBPG; XBP1; RRN3; CCDC59; PURA; FOSB; PMS1; JUN; MAFF; LEF1; MLXIP; MAFB; KLF2; DLX2; FOXD1; BAZ1A; NPM1; ETV5; FLNA; JUNB; ID2; SMAD1; ENO1; MYBL1; NR2F2; KLF10; KLF4; DMTF1; FOS; EGR2; KDM5D; PUF60