Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17535 Geldanamycin GSE70138 MCF10A Human 24h 3.33uM EID0020
Types Number Response transcription factors
Up-regulation 482 FOXO4; ZNF345; TSC22D3; ZKSCAN4; CALCOCO1; ZNF91; ERBB4; PNRC1; ZKSCAN3; CBFA2T2; TBX4; ALX3; NR5A1; HOXB3; ATOH1; ZNF117; ZBTB44; ZNF665; ASCL3; ZNF254; ZNF362; ZKSCAN1; CSDC2; HOXA3; ING4; ZSCAN9; HBP1; EZH1; BARX1; MAML3; NHLH1; ZNF154; SOX18; ZNF135; TCF15; GRIP1; HIF3A; TRPS1; ZNF768; ZNF223; ST18; RFX3; APBB1; CEBPA; SIRT2; BPTF; PPARA; TBX6; GCM1; TBX5; CDX2; ZNF33B; MYF5; FEZF2; PRDM9; ZNF214; ZNF253; CRX; POU2F3; HOXA4; IRF6; PITX3; SCAI; CBFA2T3; ARHGAP35; ZNF44; CHD2; AR; NR1H2; TRIP11; HNF4G; ZNF219; ESR2; RORC; NCOA2; CRYM; ZFHX3; RXRB; DLX4; TP73; OVOL2; MYOG; SOX3; ZNF132; MED25; CBX7; GRHL2; GCM2; ZKSCAN8; ETV3; HOXB8; ZNF467; THRB; HES2; TEAD3; HDAC5; ZFP2; THRA; ZNF682; EPAS1; ETV7; TUB; ZBTB3; LZTR1; CRTC1; RARG; NEUROD4; CREBL2; MNAT1; NEUROD2; HOXA5; NHLH2; ETV2; SMAD6; DYRK1B; ZNF74; ZNF816; RARB; ZNF471; ZNF81; POU6F1; HOXA2; ZNF85; ZNF646; CARF; MYCL; ZNF667; ZNF500; ZNF257; ZNF250; ZNF286A; POU3F4; HSF4; ZNF224; AFF2; NEUROG1; ZNF80; POU1F1; SRY; TSHZ2; TCEA2; SIM1; LYL1; ZXDB; SHOX; ID4; POU6F2; ZNF814; ZNF157; AFF3; ZNF674; CIR1; ZSCAN18; ZNF141; PDX1; ONECUT2; ZNF606; EHMT2; ZNF225; PAX4; NR6A1; EMX1; HMX1; ZNF76; ZNF492; PRDM14; TP63; PROP1; NEUROG3; JUP; ZNF41; ZNF175; HOXD1; ZNF675; HINFP; DCC; DLX5; ZNF407; TBX10; ZNF444; MSX2; ONECUT1; ZFHX2; TULP2; NFATC4; LDB1; IRF9; SIX3; ZNF778; ZSCAN31; SUPT3H; TRIM22; BCL11A; PHF1; TAF1C; FOXL1; ZIC3; PBXIP1; KLF13; GSC2; KAT2B; HOXD3; RSF1; TEF; SIX5; ZNF749; SALL2; TLX3; ZFPM2; ZNF611; MZF1; GBX1; ARID5A; SCRT1; EVX1; LHX3; ZNF695; CNOT3; CDX1; ZNF287; SOX17; ZNF350; ZNF507; TOX; SOX14; ZNF248; ZNF536; PEX14; HOXB1; ZNF613; SOX13; RAX; MECP2; SMARCD1; SPI1; TULP1; ZNF623; RYBP; MEF2C; BAZ2A; MLXIPL; HEYL; FOXD3; ZNF234; ZNF440; BAZ2B; SRCAP; TONSL; ZNF235; OSR2; IKZF3; ZNF334; ZBTB7B; VENTX; HR; CBX4; ZNF34; PKNOX2; ZNF133; ASCL2; PHIP; HOXB13; POU3F3; CIC; ALX4; ZNF506; POU2F1; POU4F3; MYOD1; TBX1; TFAP2A; BTG1; CIITA; MYF6; ZNF75D; FOXN3; HOXA6; ZNF544; SIX6; HOXB5; GFI1B; PRDM2; ZNF669; TRIM29; SMARCC2; ZNF112; RXRA; PFDN5; RBFOX2; NR1H4; ZNF358; HOXD13; WNT4; NR5A2; KLF1; GBX2; ZNF155; RFX2; ACTL6B; ZNF423; RBPJL; TBX21; SOX1; ZHX2; NFKB2; STAT2; ZNF148; BRDT; SETDB1; SOX12; VGLL1; ZNF331; FOXB1; ZNF415; DBP; HOXB2; TFAP2C; ZNF701; NEUROG2; ARNT; ZNF688; HIC1; SOX21; PRDM12; MED12; ZSCAN16; LITAF; RING1; MYCN; MXI1; PIAS4; NFAT5; ZNF205; FOXA1; OLIG2; ERBB2; NAB2; TULP4; ZNF93; HESX1; ZIC1; HSF1; MEF2D; VPS72; NEUROD1; MECOM; MYT1; PRDM10; MEIS2; FOXH1; AES; FOXJ1; TLE2; ZNF43; TFDP2; ZNF180; FOXF1; KLF5; CDIP1; ZNF264; ARID3B; HDGF; ZNF136; ZNF671; HDAC9; ZNF711; ESRRG; EP300; DDIT3; TCF25; CDYL; CAMTA1; MEOX1; PDLIM1; MEIS1; IRF7; CREB3L2; CUX2; EN1; TFEC; ELF4; ZNF12; ZBTB20; ZNF268; TAL1; EHF; ZNF580; MXD4; BRD4; MSC; CREB3; HMBOX1; PAX6; ZNF304; SSBP3; RXRG; INSR; ZFY; TERF1; NFE2; CUX1; KMT2A; TCF7L1; TRIB3; LHX1; ZNF222; TBX3; GATA1; SMARCA1; INSM1; TULP3; PBX1; EYA1; ZNF430; NR4A1; BNC2; ZNF195; THAP10; NCOA1; ARNT2; HEY1; HOXB6; NFE2L1; NKX2-2; FOXF2; SOHLH2; PLAGL1; ZNF652; TCF4; TCF7; TCF7L2; ZMIZ1; ZNF160; SIX1; TOB1; BASP1; EMX2; ZNF329; HIC2; NR1D2; NPAS2; FLI1; ZNF165; ZNF211; KDM5B; HEY2; CTBP2; ZBED2; FOXA2; HMGN3; NR0B1; ID2; MKL2; LIN28A; ARID5B; MNDA; ASCL1; ID1; GATA6; RBPJ; NR3C1; ELF3; DACH1; WT1; MEOX2; NR4A2; MYRF; ATF3; MYB; MAF; POU2AF1; GATA3; GLI2; PEG3; SOX2; TXNIP; KDM5D; TOX3; SSBP2; HMG20B; NFATC3; ESR1
Down-regulation 140 FOSL1; CCNA2; HMGA2; ADRB2; TFDP1; EZH2; MYC; TCERG1; FHL2; C1QBP; SUV39H1; TBP; RBM14; NUP62; ARID4B; BRCA1; NFKBIA; RUVBL1; MYCBP; PARP1; HNRNPD; PPRC1; EGR1; RHOA; CBFB; NFIL3; RNF138; DRAP1; CENPF; BAZ1B; DR1; BAZ1A; EDF1; IKBKAP; DDX54; YWHAB; SMARCC1; SSRP1; UBP1; BCLAF1; ELK3; GCFC2; GABPB1; ETV1; CHD1; TSC22D2; EED; CHAF1B; HMGB2; ORC2; SFPQ; HOXC6; MYBL2; RAN; RBPMS; SF1; ELF1; PRKDC; NFKB1; TCFL5; BIRC2; PSMC3IP; NRIP1; PREB; DDX5; STAT5B; RUVBL2; FOXM1; BATF3; RNF4; PA2G4; TRIM32; NPM1; HSBP1; TAF9; EGR3; KLF2; SMARCA5; HLTF; ING2; BMI1; JARID2; ZBTB24; RBL1; KMT5A; PMS1; ASH2L; PTTG1; HDAC1; LEF1; ZNF672; GTF3A; BLM; HSF2; RNF6; CCDC59; ADNP2; ITGB3BP; RBBP4; ZBTB18; NEDD8; SUB1; CRY1; RBBP7; WWTR1; UBE2I; TRIM28; ETS1; TFAM; WHSC1; ZNF593; THAP11; HMGB1; GATAD2A; ZNF146; PURA; NR2F6; FLNA; YEATS4; SAP30; DNMT3B; CEBPZ; HOXB7; ENO1; PITX1; EGR2; MTDH; KLF6; MLXIP; NRBF2; ZFP36L1; MAFB; HOXC10; SMAD1; NR2F2; IFI16; KLF10; NR2F1; PUF60; DMTF1