Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17524	Withaferin-a	GSE70138	MCF10A	Human	24h	1.11uM	EID0020

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	CREBL2; ZNF331; ST18; ZNF665; ZNF219; SOX17; ZNF91; FOXO4; ZFHX3; CBFA2T3; ING4; PRDM14; ELF5; RORC; HESX1; ZFPM2; ERBB4; PEX14; TEAD3; IRF6; RFXANK; MEIS2; PHIP; GFI1B; PNRC1; TFEC; BRWD1; ZNF43; NR4A1; TCF7; TCEA2; MEIS1; TULP3; ZIC3; CALCOCO1; PBX1; NFATC4; TDP2; ZBED2; WWC1; ID3; ACTL6B; ATN1; ZSCAN31; TCF12; BCL11A; INSR; WNT4; ZNF430; NCOA3; BAZ2B; CRYM; CREM; ID1; HMBOX1; TAL1; ZHX2; KAT2B; TGIF1; PAX6; NANOG; NR4A2; CREB3L2; HTATIP2; ZNF264; ZNF93; ATF3; INSM1; ZBTB20; TSC22D1; TRIM22; CD3D; HHEX; ARNT2; GATA6; TRIM29; IRF8; EMX2; BHLHE41; PBX3; FOXF2; KLF5; PEG3; IRF9; NKX3-1; BASP1; MYRF; TRIB3; ZBTB16; GLI2; TBX3; SOX2
Down-regulation	61	CCNA2; NRIP1; NFIL3; ATF1; HDAC2; MYC; C1QBP; HOXA10; HNRNPD; SUV39H1; NUP62; RBM14; HMGA2; CENPF; ZBTB18; ADNP2; RARA; JARID2; EGR1; SF1; ZBED4; CHD7; BMI1; SFPQ; TRIM32; SUB1; WHSC1; BRD8; HMGB2; HOXC6; RCOR1; EED; RBBP4; KLF2; TCFL5; NPM1; XBP1; HMGB1; IRF4; ELK3; HOXC10; TFAM; RUVBL2; CTR9; CBFB; HDAC1; PTTG1; MYB; MAFB; MYBL2; HLTF; RUNX3; IRX5; EGR3; ENO1; AFF1; SAP30; SERTAD2; FOXO1; BHLHE40; KDM5D