Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17518	Mitoxantrone	GSE70138	MCF10A	Human	24h	3.33uM	EID0020

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	CREBL2; RFX5; CALCOCO1; PNRC1; FHL2; TSC22D3; NFKBIA; SIN3B; CAMTA2; CBX7; ATF3; RELB; IRF6; TRIM22; SRCAP; PBXIP1; HBP1; SOX4; MDM2; RUNX1; SP2; FOXO4; NCOA2; TBX3; CSDC2; DLX4; IRF7; FOSL2; PPP1R13L; ZNF665; ZNF331; IRF1; NR1I3; MNT; TOB1; KLF11; FOSB; NR4A2; ZBED2; MYCL; ZNF226; PSPC1; BHLHE41; KAT7; ZBTB20; PLAG1; IRF9; JUNB; EP300; HTATIP2; KLF13; FOXN3; MED13; ZNF611; NFE2L3; ZBED1; ZNF14; TSG101; ATN1; ZNF652; ING4; BAZ2B; RXRA; RNF111; TRIM29; EZH1; NCOR2; PRDM2; STAT1; BTG1; HDAC5; TP63; BCL3; NFE2L1; OSR2; MXD4; LPIN2; PBX3; JAK2; ZNF160; ZNF195; HDAC4; SP110; SOX15; IRF2; NKX2-1; GATA6; PHF1; TBX21; NR4A1; ZNF430; RSF1; ZBTB43; MAFF; TFAP2C; JUN; UBE2B; ZFPM2; SIAH2; BCL10; SSBP3; ERBB4; ELF3; ZNF264; KAT2B; DDX17; BASP1; ZEB2; NANOG; BCL6; SCAND1; TCEA2; TFEC; PHF20; ZNF721; PDLIM1; TAF7; MAF; DACH1; IRF8; VDR; AEBP1; TCF4; MNDA; IFI16; MXI1; HLF; EGR2; WNT4; JUP; HMGN3; MYB; BCL11A; CREB1; ZNF423; MAGED1; ZBTB18; SOX9; CITED2; KDM5D; ZBTB38; SATB1; FOS; GATA3; ESR1
Down-regulation	98	CCNA2; TFDP1; CENPF; EZH2; BRCA1; PCBD1; FOXM1; CDK2; PTTG1; PA2G4; C1QBP; RUVBL1; MYBL2; RBM14; PARP1; MTA2; HNRNPD; NPM1; HMGB2; NFIB; SUV39H1; MYC; NFIL3; CBFB; ECD; SMARCC1; FOSL1; SSRP1; BAZ1B; RNF138; PITX1; NONO; HDAC1; CHAF1B; BLM; HMGA2; MNX1; BCLAF1; RUVBL2; DEK; CAPN15; ZNF410; DNAJC2; CNOT6; SLC2A4RG; SMARCD2; SMARCA4; TAF9B; YBX1; CCDC59; WHSC1; RBBP4; CARM1; DR1; SMARCE1; HMGA1; SFPQ; ADNP2; WWTR1; TRIB3; TRIM28; HDGF; HMGB1; AGO2; RAN; HOXC6; CBX5; TAF5; CCNC; BRIP1; GTF2I; CHD7; RBM39; JARID2; SMAD1; NR2F2; LEF1; HOXC10; NR2F1; YEATS4; NFYA; TGFB1I1; CEBPG; SOX11; ZNF146; SATB2; FOXL2; PAX5; HLTF; HMG20B; SIM2; CITED1; SAP30; BAZ1A; ZIC1; MEOX2; WT1; HEY1