Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17517	Mitoxantrone	GSE70138	MCF10A	Human	24h	10uM	EID0020

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	RFX5; ZMYM2; TRIM22; IRF6; ZNF768; PPP1R13L; TSC22D3; TSHZ2; ING4; IRF7; TRIM29; CALCOCO1; SIN3B; TP63; DAXX; SRCAP; RING1; DLX5; ZNF331; PEX14; TEAD3; CAMTA2; IRF9; TCEA2; CBX7; ZNF665; ARID5A; CDIP1; ATF3; SP100; NFATC4; ZNF117; JUP; OLIG2; RARG; NFAT5; ZNF536; HBP1; MDM2; NFATC3; OSR2; MNT; SKI; TFAP2C; SIRT2; KAT6B; HOXB1; TBX3; ZNF671; ZNF611; HOXD1; SNAI2; ZNF264; JUN; SALL2; OVOL2; SP140L; PHF1; BTG1; ZBED2; PBXIP1; CERS4; SP110; KLF13; ERBB2; FOSL2; GRHL2; TRPS1; MAF; HMBOX1; NCOA2; STAT6; HLF; RUNX3; MXI1; ZNF415; HDAC9; ZSCAN18; NCOR2; KAT2B; STAT1; TOX; ZNF350; EHF; HOXB2; TGIF1; ID4; ZNF512B; KLF11; ZBTB20; MYCN; SOX9; IRF8; ARNT2; PEG3; HTATIP2; MEIS1; GATA6; TCF4; TSC22D1; ZNF91; NKX2-1; ZNF423; MYRF; POU2AF1; TRIB3; TOX3; BHLHE41; HEY1; TXNIP; GLI2; FOS
Down-regulation	83	CCNA2; EZH2; BRCA1; CENPF; TFDP1; TCERG1; SUV39H1; PTTG1; HMGB2; RBM14; CDK2; BLM; HDAC2; C1QBP; HNRNPD; FOSL1; FOXM1; BCLAF1; BAZ1B; HMGA2; MYBL2; HMGB1; CHAF1B; ITGB3BP; DEK; ATF1; PITX1; NPM1; SSRP1; WHSC1; CHD7; RUVBL2; SFPQ; SUB1; BRD3; CCDC59; TAF5; BRIP1; SAFB2; RAN; PSMC3IP; EDF1; RNF138; RBM39; ING3; EED; PIR; TAF9B; AGO2; HSF2; RBBP4; TTF1; CBX5; E2F8; YEATS4; HMG20B; MBD2; RBPMS; HOXC6; HMGB3; ARNTL; CCNC; SAP30; TRIM28; HOXB7; HLTF; DNMT3B; SMAD1; BMI1; NR2F2; TBL1X; MYB; SOX11; HOXC10; BHLHE40; WWTR1; NR2F1; MYT1L; LEF1; ASCL1; CALR; SATB1; KDM5D