Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17493 Torin-1 GSE70138 MCF10A Human 24h 0.12uM EID0020
Types Number Response transcription factors
Up-regulation 66 SOX4; CREBL2; HMGA2; PNRC1; CALCOCO1; RELB; ZNF665; STAT2; NFKB2; TGFB1I1; ZNF224; IRF6; ZNF358; REL; ZNF611; KLF7; ERBB2; JUP; PPP1R13L; AES; ZNF160; NAB2; ZMIZ1; MECOM; SOX12; ZNF91; ZBED2; HBP1; SRCAP; TCEA2; PBXIP1; SOX17; NFATC4; MEOX2; HDAC9; HMGA1; BCL11A; NFAT5; ZNF83; STAT6; ATN1; GRHL2; BCL3; KLF11; SALL2; SATB2; ZNF652; ARNT2; ID1; HOXD1; FLNA; KLF5; ZNF423; BTG1; INSR; IRF9; TRIB3; TGFB1; ZBTB20; SOX11; EMX2; VPS72; HEY1; SOX9; KDM5D; CREB1
Down-regulation 42 CCNA2; MYCBP; TFDP1; SUV39H1; C1QBP; GTF2A2; EZH2; SUB1; NFIL3; RBM14; ETV1; MYBL2; TFAM; NUP62; RNF6; EED; HMGB2; ZNF200; FOXM1; HSF2; CENPF; HMGB1; CHD7; BCLAF1; RBBP7; ILF2; PIR; YEATS4; CRY1; HOXC6; YWHAB; PSMC3IP; PTTG1; RBPMS; RNF14; PURA; HLTF; NR2F1; NRBF2; CITED2; WT1; PEG3