Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17489 Torin-1 GSE70138 MCF10A Human 24h 10uM EID0020
Types Number Response transcription factors
Up-regulation 186 PAX8; TSC22D3; SOX4; PNRC1; FHL2; HDAC6; RELB; CALCOCO1; ZNF117; ING4; CDK7; NR2C1; ZNF665; HDAC5; HBP1; AFF2; ZNF688; ZNF91; ZMIZ2; GTF2IRD1; PAX2; FOXO4; CIR1; HINFP; ZNF768; EZH1; SRCAP; ZNF154; PBXIP1; SCAI; ZBTB44; KLF7; CBFA2T2; DLX6; MXI1; ERBB4; DLX4; CSDC2; SALL1; IRF5; ZNF506; APBB1; ZNF250; DLX5; ZSCAN18; ZNF611; ZNF358; IRF6; ZNF33B; STAT2; KLF3; BTF3; ZNF160; MED12; ZNF354A; CARF; CBX7; PROP1; ZFHX2; ATF2; SIX3; KLF6; HDAC9; GBX2; TFDP2; ZNF177; REL; HOXB13; MTF2; MED15; TCF7L1; RORC; SMAD6; ID4; EMX2; IRF9; ZNF623; YEATS2; ZHX2; ATF4; CTNNB1; ZNF337; ZBED2; ZNF500; ZNF701; OLIG2; SIRT2; MEF2C; E2F5; PAWR; SETDB1; CDIP1; REPIN1; HOXB1; BPTF; PHF1; CNBP; ZNF93; ARID3A; ERBB2; PQBP1; CUX1; SMAD3; ZBTB43; ZNF415; CERS4; ZNF536; ZNF430; ELF4; TCF7; ST18; PFDN5; ZNF721; MXD4; LYL1; SOX17; HSF1; TLE2; KLF13; L3MBTL1; AES; HOXD1; ZNF32; ELF3; JUND; PDLIM1; ZNF195; ZNF85; TAL1; ZNF133; LPIN2; ATF3; CREB3L2; ZNF83; FOSB; ZFP36L2; NFE2L1; ZNF43; NFATC4; NKX2-1; CTBP1; STAT6; TCEA2; KLF11; BTG1; VPS72; FLI1; SSBP3; HIVEP2; BCL11A; SALL2; HMBOX1; DLX2; IRF1; FOXO3; BAZ2B; PCGF3; ZIC1; FOXN3; BHLHE41; TRIB3; FOXE1; NPAS2; TCF3; NCOA3; INSR; ESR1; LITAF; ZFP36L1; TRIM29; ID3; ZNF532; ARNT2; JUP; TLE1; MYRF; SOX9; TLE4; HOXC10; HOXB2; MECOM; POU2AF1; INSM1; TBX3; HMG20B; ID1
Down-regulation 98 MYCBP; TFDP1; PARP1; CCNA2; RUVBL1; FOSL1; SUB1; RBM14; TBP; BRCA1; EZH2; ECD; GTF2A2; GMNN; RNF138; C1QBP; DNMT1; EGR1; BCLAF1; EED; NUP62; MYBL2; ETV1; SFPQ; PITX1; IKBKAP; WDHD1; NFIL3; CHAF1B; TFAM; DNAJC2; PA2G4; CBFB; HNRNPD; NR2F6; RNF6; PPRC1; PRKDC; CEBPZ; ITGB3BP; ILF2; ATF1; PTTG1; LZTS1; HMGB2; WDR77; PMS1; ISL1; DEK; SMAD5; SSRP1; ABT1; CENPF; ADNP2; PTRF; ZBTB1; NFIB; BMI1; ZBTB18; HSF2; ING2; RBBP7; HSBP1; EGR3; ASH2L; SREBF1; BCL11B; MED1; CREM; MED21; ING3; PURA; PLAGL1; PRRX1; TRIM28; PSMC3IP; TRIM24; HLTF; BHLHE40; SMARCA2; WWTR1; KLF10; MEIS2; RUNX3; SAP30; BAZ1A; PIR; KLF2; BBX; SMAD1; NR2F1; KLF9; NR2F2; IRX5; IFI16; PBX1; TOX3; CREB1