Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17480 Gsk-2126458 GSE70138 MCF10A Human 24h 0.37uM EID0020
Types Number Response transcription factors
Up-regulation 367 TSC22D3; CALCOCO1; SOX4; CREBL2; FOXO4; HBP1; ING4; NR2C1; PNRC1; FOXN3; HOXA10; HDAC6; MYCL; CIR1; KDM5A; BTG1; ZNF665; CSDC2; SIN3B; NR1H2; HDAC5; CBX7; EZH1; NR1I3; ZBTB16; AEBP1; NR5A1; ZNF362; SP2; ZBTB3; PAWR; ZKSCAN1; SALL2; OSR2; PPP1R13L; ZNF33B; ZNF688; ZNF500; BPTF; HDAC7; ZNF345; NHLH1; ZNF34; ZBTB43; ZNF224; SPI1; ARID4B; EP300; CEBPD; JAK2; SCAI; ZKSCAN4; HNF4G; SUPT4H1; IRF9; NFE2L1; NAB2; ZNF304; CRTC1; BACH1; ZBTB44; PBXIP1; ZFPM2; BAZ2A; PHIP; TEAD3; HOXB3; ZNF623; ZHX2; VGLL4; FOXN1; ESR2; THRB; ERBB4; TCF15; HINFP; RORA; PRDM2; ZBTB39; ZNF506; HIF3A; NEUROG3; HSF4; ALX3; MXI1; INSR; SIM1; ZNF117; TSHZ2; CERS4; KLF3; AFF2; ZNF254; FEZF2; ZNF44; NFIL3; CRX; UBE2B; SOX18; ARID5A; FOXO3; BRWD1; ARID4A; ZNF219; APBB1; TCF7L2; ZNF768; EMX1; NFE2L3; ZNF671; ZNF394; TBX5; ZNF76; SKI; SP100; MED13; TCEA2; ZNF91; NEUROG1; IRF6; DYRK1B; BTAF1; BCL11A; CITED2; ZNF154; DLX4; KLF9; KLF7; ZNF175; ZNF132; RORC; TP63; MYOG; ZNF184; ATF3; ARNT; SRCAP; ZNF12; MED23; NFKB2; E4F1; ID4; ZNF778; RING1; ZNF358; KLF13; JUP; ZNF354A; TULP3; ZNF701; IRF8; PHF1; RXRB; ZNF135; MEF2D; NR5A2; MED12; HOXD13; FOSL2; KLF11; CBFA2T3; SOX5; ZNF611; STAT6; ELF4; WNT4; ZNF264; TAF1C; PLAG1; ZNF24; RARG; ZNF16; CHD2; ARID1A; ZNF235; SMARCC2; ATOH1; IRF7; CNOT2; TRPS1; MNDA; ZNF426; ZNF430; NFATC4; TCF7; BHLHE41; RBPJL; CARF; NCOA2; FOXH1; ZNF225; EVX1; SMARCD1; TAF11; MEF2C; ZNF32; ZNF124; TFEC; SOX13; GON4L; CAMTA2; TRIM29; ZNF222; ZNF14; ZSCAN18; ZXDC; ZNF83; SMAD4; TAL1; SSBP3; MZF1; ZBTB7B; ZBTB20; ATF7IP; PCGF3; HIC1; HOXB13; TFAP2C; FOXJ2; RSF1; ZNF136; HMBOX1; RAX; PEX14; HOXB1; HOXD1; ZMYND8; THRA; PIAS1; CBX4; CDK9; ZNF223; REL; MAFF; TULP1; SRY; ZNF764; KAT2B; PRDM12; KLF4; CEBPE; PSMC3; ERBB2; BARX1; CTBP2; ZNF141; ZSCAN16; KLF6; ZNF292; FOSB; TBX1; TSG101; SOX3; PKNOX2; ZNF331; HIC2; DLX5; ZNF268; MED14; GATA6; CDIP1; TRIM22; PEX2; ZIC3; THAP10; NR4A2; NFAT5; ZMIZ2; SHOX2; ZNF419; FOXO1; NFATC3; SOX17; ARL2BP; L3MBTL1; ZNF467; WWP1; ZNF544; TBX21; ZNF160; ZEB1; BAZ2B; AHR; ZNF217; ZNF112; DDIT3; NR1H4; TFEB; TGFB1I1; TXNIP; MITF; HIVEP2; SP140L; MEIS2; GATA1; HOXB2; ZNF189; TGIF1; INSM1; ZFY; MEOX1; HLX; TFDP2; GRHL2; ZBED1; NCOA3; ZNF148; SP110; KLF5; NR4A1; NR1D2; NFATC1; ZNF140; ATN1; MEOX2; TOX3; ZNF423; HOXC4; LMCD1; ZNF580; FOXE1; ZFP36L2; TCF7L1; ARNT2; IL16; HOXB5; BNC2; PHF20; ZNF652; ZNF93; ST18; PBX1; NR1H3; APEX1; HTATIP2; DAXX; NPAS2; HDAC9; TDP2; ZNF350; CUX2; TCF4; ZNF551; MAFB; AFF1; TRIB3; HMG20B; TCF21; KLF2; TOB1; BRD4; SPIB; EMX2; TLE1; PBX3; CRYM; MYBL1; MAF; ARID5B; SNAI2; KDM5D; MYRF; MEIS1; ZNF586; NR3C1; FOS; SSBP2
Down-regulation 106 FOSL1; MYCBP; TCERG1; PARP1; TFDP1; CCNA2; MYC; C1QBP; RUVBL1; PITX1; RBM14; HDAC2; EZH2; NUP62; BRCA1; GTF2A2; ATF6; HMGA2; CBFB; HNRNPD; PPRC1; RAN; HSBP1; HLTF; EGR1; DNAJC2; BCLAF1; WDR77; RUVBL2; PA2G4; HES1; DRAP1; TAF9; IKBKAP; MYBL2; ING2; MSX1; MYBBP1A; SUB1; SMARCA5; RBBP4; DEK; EDF1; PTTG1; CEBPZ; SUV39H1; ILF2; GABPB1; YBX1; KMT2B; URI1; RFC1; RNF4; DR1; ELK3; SSRP1; TRIM28; NPM1; RBBP7; PRKDC; ZNF146; CCNE1; TP53; SFPQ; EED; BMI1; SF1; ITGB3BP; HDGF; TFAM; XBP1; STAT3; YWHAB; CNOT1; HOXA5; PMS1; EGR4; UBE2I; UBE2L3; CHD7; HMGB1; DNMT3B; BHLHE40; SREBF1; HDAC1; ENO1; CTR9; TAF9B; CRY1; SMAD7; TSC22D2; POLR2A; WWC1; BAZ1A; ETS2; SOX9; IRX5; NR2F1; HMGN3; RREB1; ID1; SIM2; PUF60; LEF1; TRIP6; SAP30