Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17479 Gsk-2126458 GSE70138 MCF10A Human 24h 1.11uM EID0020
Types Number Response transcription factors
Up-regulation 220 TSC22D3; SUV39H1; SOX4; HDAC6; PNRC1; FOXO4; ADRB2; CALCOCO1; HBP1; ZNF768; CIR1; CREBL2; EZH1; NFIL3; HDAC5; ING4; VGLL4; PQBP1; NR2C1; CBX7; ZKSCAN4; ZBTB16; TFE3; DLX4; ARID4B; FOXN3; ZNF688; HINFP; ZNF345; PRDM2; NR1I3; CRX; TAF1C; RORC; CRTC1; CEBPD; THRB; PHF1; CBFA2T2; BTG1; ARID5A; IRF6; CBFA2T3; PHF20; ZNF467; CARF; FOXO3; SCAI; NFE2L1; BPTF; MECP2; TRPS1; AFF2; ZNF33B; MXI1; TCF7L1; PBXIP1; SRCAP; SPI1; HOXB13; YEATS2; KLF3; SSBP3; RXRB; NCOA2; BACH1; ZFHX3; ATF3; ZNF510; SIM1; RBPMS; ELF4; HOXD13; ZNF358; ZNF665; STAT2; TP63; EPAS1; ZNF354A; THRA; TCEA2; PPP1R13L; ZNF444; PEX14; SP2; HOXD1; AIP; ZNF500; KAT8; SUPT4H1; ZNF117; IRF9; CAMTA2; NR1H3; ERBB2; NFATC4; PSPC1; AES; OSR2; TEAD3; DLX5; TFAP2C; TSG101; HOXB1; ZNF264; NFKB2; TBX21; SMARCC2; TLE2; PIAS1; ZNF75D; SMAD6; TRIM22; ZNF611; SETDB1; MYCL; ZMIZ2; PHIP; ZNF217; ZNF337; MITF; ZNF652; PRDM14; AHR; ZNF91; EP300; JUP; LYL1; TSC22D1; ZNF536; ZNF219; MZF1; SP100; CITED2; SALL2; SOX12; MED12; ZNF623; ZNF133; ZFP36L2; TCF25; EN1; RARG; DDIT3; TXNIP; ELF3; TCEB2; TFEC; TFDP2; MNDA; BCL11A; KLF4; MBD2; NCOA4; HIC2; ZNF304; ZNF606; TGFB1I1; JAK2; ZIC3; LPIN2; TRIM29; TAL1; HSF1; SSX1; GRHL2; KAT2B; HDAC9; MAZ; ERBB4; UBE2B; HIRA; CD3D; GFI1; KLF9; MEOX2; ZSCAN18; ARNT2; SAP18; RXRA; LMCD1; RBPJ; SOX13; BCL6; STAT6; TGIF1; CUX2; ZNF350; TCF7L2; ZHX2; KLF11; KLF13; FOXF2; HTATIP2; INSR; ATN1; HLF; FOXO1; PPARGC1A; TLE1; CRYM; SOX10; ARID5B; MAF; TRIB3; WNT4; ZBTB20; ZNF512B; SNAI2; HEY1; VPS72; LITAF; FOXG1; IRF8; HMG20B; MAFB; MYBL1; SSBP2; FOS; KDM5D
Down-regulation 103 FOSL1; MYCBP; TCERG1; PARP1; TFDP1; CCNA2; MYC; C1QBP; RUVBL1; RBM14; PPRC1; HDAC2; EZH2; NUP62; GTF2A2; BCLAF1; HES1; CHAF1B; WDR77; ECD; PA2G4; HNRNPD; EGR1; MYBBP1A; PITX1; SFPQ; ILF2; GABPB1; RAN; BRCA1; TAF1A; MYBL2; CRY1; CHD7; CBFB; EED; CNOT1; DRAP1; DNAJC2; SMARCA4; SF1; WDHD1; PRKDC; IKBKAP; TFAM; SMARCA5; BAZ1A; SSRP1; PREB; RUVBL2; CEBPZ; SUZ12; RBBP4; CTR9; UBP1; NFKB1; SUB1; PSMC3IP; PMS1; NEDD8; DR1; TRIM28; HLTF; LEF1; EGR4; HSF2; NFYA; NR2F6; SMARCA2; WT1; EDF1; CCNE1; EGR3; MED1; HOXA5; NPM1; RNF138; URI1; PEG3; ELK3; HMGB1; PAXBP1; PTTG1; ENO1; MTF2; IRX5; ZBTB18; RBBP7; NFIB; DNMT3B; RBBP8; IRF4; ING3; TSC22D2; PURA; HMGB2; HOXB6; HOXC6; ID3; PUF60; NR2F1; DACH1; ID1