Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17455 Jnk-9l GSE70138 MCF10A Human 24h 3.33uM EID0020
Types Number Response transcription factors
Up-regulation 748 ZNF345; ERBB4; CBFA2T3; ZNF91; ZNF331; EMX1; ZBTB44; NHLH1; SOX18; ASCL3; CSDC2; THRB; TAF1C; NEUROD4; FEZF2; ZFPM2; SOX17; ZKSCAN4; ZNF135; NEUROD2; RFX3; MEF2C; ZNF154; ONECUT2; CNOT3; ZKSCAN3; ZNF667; MED25; CHD2; WHSC1L1; SNAI1; SCAI; ZNF132; HES2; MECP2; TBX5; NEUROG1; ZIC4; TBX6; DLX5; NR5A1; ZBTB3; ZKSCAN8; PAX2; CCNH; PRDM9; ZFP2; ALX3; EP300; ZNF768; RFX1; SSX7; EYA3; ZNF34; POU6F1; ZNF362; ZNF79; ZNF695; AFF2; NR5A2; ZNF507; KLF3; RARG; HOXA3; LHX3; FOXE3; ZNF682; NEUROD1; SHOX; POU6F2; ZSCAN2; HOXB1; ZNF549; ID4; ZNF665; ZNF492; PRDM1; ZNF225; ZNF235; ING4; ATOH1; PRDM12; HDAC5; HOXB8; DLX6; ZNF304; ZNF467; HOXC8; ETV3; SRY; SCRT1; ZNF254; NEUROG3; GCM1; DCC; ZNF506; TP73; NEUROD6; ZNF442; PAX1; ZNF606; ZNF440; RFX2; HOXD3; VGLL1; SIX3; ZNF701; TBX4; ZBTB43; NEUROG2; NR1I3; CIR1; NFATC4; SALL1; ZNF529; TBX2; NR1H2; ZNF221; ONECUT1; ZNF550; NAB2; ZNF264; ZSCAN18; GRIP1; OSR2; MAFK; ZNF257; ZNF814; ZNF623; PROP1; TRPS1; EPAS1; POU3F4; PRDM14; ARID3B; ZNF223; CRX; ZNF81; ZNF426; ZNF175; EZH1; TBR1; TBX1; POU2F3; HEYL; DLX4; MYNN; ZNF250; ZNF85; ZIM2; KLF8; IRF6; HOXD12; PAX4; ZNF471; ZNF778; ZNF136; KLF13; HNF4G; AR; ZNF343; ZNF816; ALX4; MYCL; DOT1L; AFF3; NR6A1; MAML3; TLX1; VENTX; PAX7; SP4; ZNF749; THRA; HOXA6; CDX1; ESRRB; LMX1B; IKZF3; TSC22D3; TAF6L; ZNF557; ZNF350; GBX2; CBX2; ZNF780B; MLLT1; PRDM2; CUX2; ZNF444; TEF; ZNF500; NKX2-5; E2F4; SSX3; MED31; HLX; IKZF2; SOX3; ZNF117; ZNF573; GCM2; TLX3; FOXP3; IRF9; ZNF14; ZNF324B; E4F1; PAX3; TONSL; ZNF675; ZNF157; ACTL6B; SMAD9; SHOX2; ZNF394; ZNF155; ZNF407; ZNF674; ZNF141; MED17; SPI1; NRL; ZNF80; REL; ZSCAN9; ZBTB39; PNRC1; SOX14; PPARA; LZTR1; NPAS1; ZNF253; TULP1; BNC1; ZNF214; CDX4; ZNF415; CAMTA2; TFDP3; LMCD1; RBPJL; ZNF391; FOXL1; HIF3A; SMARCC2; ZNF208; HNF4A; LHX6; ZKSCAN1; ETV2; POU3F3; ZFP30; MZF1; HOXC5; BARX1; CARF; HHEX; CALCOCO1; SOX21; NKX6-1; TCEA2; TAL1; ZNF671; HINFP; LBX1; CIITA; PITX3; ZNF286A; HNF1B; SMARCD1; RORC; ZFHX3; BCL11A; PKNOX2; ZNF669; MAK; PBX2; FOXB1; POU1F1; HIC2; NHLH2; ESRRG; ZXDB; ZNF142; HDAC9; FEV; TULP2; VHL; ZNF770; SOHLH2; KLF15; CBX4; ZNF273; ZSCAN32; ZFHX2; GFI1B; SIX6; POU4F3; ZNF197; MDM4; PRRX1; HOXD9; PRDM10; GSC2; ZSCAN31; PRDM5; RING1; GFI1; EN1; ZNF613; SALL2; ZNF12; HIC1; ST18; FOXJ1; IFNB1; PDX1; NOCT; FHL5; ZNF668; ZNF74; DBP; HOXA2; WT1; ZNF430; DYRK1B; MSX2; ZNF174; MEIS2; SOX1; ATF7; HBP1; TGIF2; HEY2; GATA2; MYF5; HSF4; TFEC; TAF4B; OVOL1; GBX1; ZNF180; ZNF43; PRDM16; GTF2A1; ZNF580; TUB; ASH1L; ZNF419; RARB; SOX5; ELF4; NR4A3; ZNF222; ZNF711; ZNF493; FOXH1; ZNF287; HDAC6; HESX1; THAP3; DMRT1; ZNF484; ZNF556; GMEB1; MXI1; ZNF234; TFAP2B; ESR1; SSBP3; NFKB2; RAX; EVX1; BRWD1; GMEB2; ZHX2; ZNF324; CDIP1; TEAD3; ZNF423; ZNF134; ZNF835; ZNF75D; MAPK8IP1; NKX2-8; ZBTB7B; ZNF710; ZNF696; TFAP2A; TAF11; IKZF4; RXRG; ESR2; BAZ2A; SIM1; ZNF93; HDAC11; PRDM13; SKIL; MDM2; RORB; FOXN1; TLX2; HOXB5; LDB1; CRTC1; FOXD3; SKI; EHMT1; ZNF536; ZNF35; THAP9; HMGXB3; PGR; OLIG2; NKX3-2; NFE2L2; SNAPC4; RYBP; PEX14; INSR; ATF6B; MXD3; ZNF771; WNT4; LYL1; ZNF329; SP2; MYOD1; ZNF571; ZNF41; E2F1; HAND2; THAP7; BACH1; ARID5A; BARX2; ZNF460; ARID3A; CEBPE; ARHGAP35; PEG3; ZNF8; ZNF177; TWIST1; TCF21; ZBTB7C; MYEF2; ZXDC; ZNF408; MAP3K10; HOXD13; KAT2B; EMX2; ZNF274; PML; ZNF551; NR1H4; FOXC2; HMBOX1; TBL1Y; BPTF; NR0B2; E2F8; ZBTB48; MBD4; POU2F2; BRDT; ZSCAN16; ASCL2; CBX7; ZNF232; PHF1; BRF2; CREB3L2; ZNF652; ZNF211; SIX5; ZNF224; TCF4; ZNF334; KLF11; BRD4; ZNF688; ZNF33B; TBX10; YBX2; GRHL2; CBFA2T2; PAX5; ETV7; SIN3B; VSX1; TSHZ2; INSM1; TGFB1I1; GATA1; SRCAP; AIRE; ZNF611; ZNF268; JUP; AHR; TBX21; ZBED2; TRAF6; ZNF219; APBB1; DLX2; FOXI1; ZIC3; CCNT1; FOXF1; L3MBTL1; CBX8; ZNF787; HAND1; ARID1A; PHOX2A; HOXC11; ZNF124; HNF1A; SUPT3H; ZNF10; MNDA; IRF5; ZNF112; FOXL2; CREBZF; ZNF44; TRIM22; KLF7; FOXE1; SSX1; VAX2; SMARCA1; HR; HIPK2; HOXB13; UTF1; JUN; MED15; MEF2D; POU4F2; HMX1; ZNF552; ZNF16; KAT6B; ELF2; SP1; ZNF215; ZNF629; MEOX1; ZNF239; ZBTB17; TULP3; ZEB1; PIAS4; ZNF165; ZKSCAN7; NFIC; HOXD1; KAT2A; PAX8; ATF2; CBX6; TBX19; ZNF354A; NR2E1; IRF8; CEBPD; NFIX; TAF5L; HOXB2; MED12; ZNF587; HMGXB4; MAFB; EN2; CHD9; NACA2; BNC2; MEN1; ZNF512B; HSF1; PCGF1; SUPT6H; MBD1; ELK4; STAT2; LHX1; TFEB; RSF1; ZNF764; PTRF; ZNF358; MSC; ZFX; CERS4; WWP1; TCF7L2; TGFB1; ZNF83; ZBTB6; ASCL1; IKZF5; NR4A2; ZBTB16; TAF1; ZNF226; ZNF654; ZNF184; SMAD6; ERF; MYCN; ZNF195; POU3F2; PAX6; ZNF24; KLF1; RARA; LHX2; MAFG; SOX12; KDM5C; MYT1; OVOL2; SP140L; LMO1; TRIB3; ZFY; SMAD7; ZNF205; ARID5B; SPIB; HIPK1; THAP10; ZNF22; DACH1; PIAS1; RORA; CDK9; KLF9; GATA6; CRYM; MYRF; SOX13; ARL2BP; VPS72; TXNIP; ETS1; ZNF3; ZNF432; SPDEF; ZBTB20; TCF3; MEOX2; FOXJ2; HEY1; MAFF; BHLHE40; ATF3; THAP11; ZNF107; HLF; TBX3; MECOM; ZNF468; ZIC1; MSX1; AEBP1; RUNX3; FOXN3; SP100; ZNF516; PROX1; SUMO1; BACH2; NKX2-2; ATN1; MED13; MITF; SP140; HOXC4; ZNF813; NFE2; CCNE1; NFATC1; SNAI2; ZNF589; ZNF148; FOSB; PHIP; ARNT2; CD3D; ZFP36L2; TCF7L1; FOXA2; ZNF140; SOX2; CREM; HIRA; BTG1; TCF7; TRIM24; EHF; MXD4; POU2AF1; NR0B1; SSBP2; NCOA3; FOSL2; KLF4; FOXF2; FLI1; ERG; NKX2-1; NFAT5; NANOG; BCL3; PBX3; TGIF1; MTF2; SMAD1; PPARD; TFAP2C; TDP2; NFATC3; EYA2; ZNF586; GLI2; NFE2L3; HOXB6; KLF10; LIN28A; FOS; ID3; MEIS1; ID1; PBX1; PLAGL1; MYBL1; E2F2; MAF; SOX9; IKZF1; CREB1
Down-regulation 170 CCNA2; MYC; HDAC2; TCERG1; ADRB2; GTF2A2; NUP62; ATF6; EZH2; RBBP4; SMARCC1; ATF1; CDK7; IKBKAP; TBP; RBM14; PARP1; MYCBP; TFDP1; BAZ1B; RAN; UBE2I; HOXA10; NFIL3; EDF1; CENPF; NRIP1; PA2G4; BMI1; NR2F6; SREBF1; DEK; HNRNPD; PSMD9; ZNF146; CRK; C1QBP; ECD; UBP1; HOXA5; BRD3; NELFB; JARID2; ZMYM2; ORC2; SMARCE1; CNOT1; USP22; ENO1; CBX3; FOXJ3; YBX1; NEDD8; PITX1; BRD8; SMARCA5; FHL2; ELF1; NPM1; DNMT3B; HMGB1; XRCC6; CBFB; TRIM16; HSBP1; PBRM1; BLM; PTTG1; NFIB; DNAJC1; RFX5; SF1; GTF2IRD1; TLE1; CTR9; SSRP1; PRKDC; NONO; BCLAF1; DNAJC2; HOXC6; NCOR2; GTF3A; TFAM; URI1; HOXB7; TAF10; ZNF672; ZBTB24; RBBP7; TAF9; DDX5; RFC1; TRIM27; NCOA6; RNF6; FLNA; STAT5B; CARHSP1; TBL1X; PMF1; ATF4; RBPMS; AATF; SFPQ; NCOA4; TCEA1; MED4; RNF14; TP53; HDAC1; ENY2; TRRAP; RBM39; XBP1; PSIP1; MTDH; PHF2; YBX3; PUF60; HMGB3; HLTF; DR1; WHSC1; PURA; CNBP; CEBPZ; MAGED1; SMARCA2; BCL11B; BAZ1A; CTNNB1; BASP1; RUNX1; TSC22D1; SIAH2; SND1; APEX1; FOXM1; SIX2; MED1; GATAD2A; PMS1; ASH2L; ERBB2; RUVBL2; FOXD1; CDYL; PHF20; SAP18; KLF5; UBE2B; NRBF2; STAT6; SAP30; JUNB; TBL1XR1; MYBL2; RREB1; SIX1; ZBTB38; KLF2; HMGN3; KLF6; HMGB2; NR2F2; TRIM29; TRIP6; EGR3; KDM5D