Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17426 Canertinib GSE70138 MCF10A Human 24h 0.04uM EID0020
Types Number Response transcription factors
Up-regulation 201 TSC22D3; RFX5; FOXO4; NFKBIA; ZNF665; TRIM29; SOX4; BTG1; ZNF768; ATF3; PBXIP1; KDM4A; ZKSCAN1; PNRC1; VGLL4; CALCOCO1; CREG1; MEIS1; HDAC5; E2F5; ING4; TRPS1; IRF6; ZNF358; HDAC7; TEAD3; MNT; ZNF44; ZNF652; TAF5L; BPTF; ZNF264; ZNF136; ZNF195; REL; HMBOX1; NR5A1; NCOA2; RING1; OSR2; RARB; CREBL2; TRIM22; CSDC2; NFIL3; SIN3B; HES1; ESRRA; TSHZ2; ZNF611; AES; NFE2L1; ZNF3; CUX1; STAT5A; IRF9; ZMIZ1; NR1H2; ZNF536; ID2; ZFHX3; ARID1A; DLX5; MZF1; CARF; ZNF14; MYCN; ZNF430; SREBF2; PBX1; CEBPD; ZNF34; ZNF669; SRCAP; SUPT7L; TCF25; ZNF688; TCF7L2; HBP1; TRIM16; INSR; MDM2; ZNF268; ZNF426; ERBB2; PEX14; ZNF91; TCF12; ZNF160; ZNF117; PDLIM1; NCOA4; FOSL2; FOXN3; ZNF394; HIVEP1; BCL6; ERF; ZNF33B; ZNF623; SALL1; BAZ2B; MEF2D; BRD4; FOXO3; MEIS2; ZSCAN31; ZNF331; GATA6; MEF2C; SSBP3; MED17; PLAGL1; WNT4; HIC2; ZNF12; SREBF1; MYCL; NCOR2; PLAG1; TCF7L1; SIX2; EPAS1; RARG; TFAP2A; TCF7; MED13; ELF3; ZBTB43; TP63; LITAF; FOXJ1; STAT6; JUNB; BBX; MECOM; TOX3; ISL1; ZNF124; L3MBTL1; BRD2; KAT6B; DDIT3; HOXB2; HOXD1; PEG3; SALL2; AR; RXRA; ZBED1; NFATC4; ETS2; ELF4; TP53; CHD9; MXI1; MITF; PIR; MAF; JUP; SNAI2; FOXO1; EYA1; HIPK1; ID1; TLE1; JUND; MNDA; TXNIP; ZNF415; TFEC; TCEA2; HTATIP2; FOSB; AHR; HDAC9; ASCL1; ZNF93; KAT2B; FOXC1; ZNF350; FOXF1; INSM1; EYA2; EHF; ZNF532; HEY1; EMX2; KDM5C; MEOX2; KLF4; ID3; BCL11A; BHLHE41; RUNX3; NR4A2; MYRF; DACH1; ARID5B; ESR1; SSBP2
Down-regulation 88 CCNA2; FOSL1; HMGA2; BRCA1; EZH2; SUV39H1; PTTG1; CENPF; TFDP1; CDK2; HMGB2; HNRNPD; CHAF1B; FOXM1; DRAP1; RUVBL1; MYBL2; PARP1; PA2G4; GABPB1; DEK; NUP62; CAPN15; TAF1A; WDHD1; PSMC3IP; ETV1; NFKBIB; C1QBP; RBM14; NFIB; EED; WHSC1; UBE2I; NOC2L; POLR3F; RBL1; BCLAF1; RUVBL2; ITGB3BP; ING2; ETV4; CRY1; CCNC; ILF2; PTRF; EDF1; ZMYND11; CCNE1; HMGB1; TAF9; XRCC6; BATF3; ZFPM2; PSIP1; NEDD8; CNOT6; TBL1XR1; SSRP1; TEAD4; BMI1; CEBPZ; HMGA1; SUB1; ELK3; NPM1; DNMT3B; EGR3; TAL1; TRIM28; CBFB; FOXE1; HHEX; MYBL1; ID4; AEBP1; BAZ1A; HLTF; MYT1L; POU4F1; IFI16; HOXC10; ZBTB18; SAP30; PPARG; HOXC6; SMAD1; KDM5D