Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17411	Celastrol	GSE70138	MCF10A	Human	24h	1.11uM	EID0020

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	TSC22D3; ECD; PIR; TRIM16; DDIT3; ZNF254; FOXO4; VGLL4; SCAND1; TP63; SOX2; ZNF141; IRF3; EN1; TRIM29; SOX3; BRCA1; TCF7; MAFG; ZNF117; ZNF682; EBF2; PRDM14; HOXD1; HDAC5; PAX9; ZNF358; ELF3; ZBTB16; MNT; CERS4; ZNF226; E2F3; AR; TCF25; CBFA2T3; ING4; SPI1; MAGED1; ZNF580; ZNF536; NR0B1; CALCOCO1; TGIF1; SP140; KLF5; ELF4; CRYM; SUPT3H; PGR; ZNF33B; DLX5; ELF5; ZNF302; FOXG1; CREM; ZIC3; ZNF85; PHF20; ZNF711; ZNF611; ZSCAN31; VGLL1; CREB3L1; IRF6; NCOR2; RNF141; ATF4; NFE2L1; NCOA3; TOX; PHIP; TFEC; PIAS2; MEOX2; TRIM22; MSX1; ZNF423; HTATIP2; ERBB4; SOX17; STAT6; PAX5; IRF9; FOXO3; ZNF91; NKX2-1; FOSL2; HMGN3; BCL6; NKX3-1; SHOX2; NKX2-2; TFAP2C; RUNX3; INSM1; BTG1; ZMYND8; INSR; BHLHE41; MYCN; POU2AF1; ZIC1; ATF3; BCL11A; JUP; KDM5A; TBX3; ASCL1; HEY1; ARNT2; TRIP6; BASP1; FOS
Down-regulation	112	CCNA2; CREG1; TFDP1; HMGA2; ADRB2; NFKBIA; IKBKAP; CENPF; NRIP1; RUVBL1; FOSL1; TCERG1; CDK2; SUV39H1; C1QBP; HDAC2; HNRNPD; PARP1; GMNN; HOXA5; SMARCA4; CBX3; MYC; BCLAF1; BAZ1B; EZH2; CAPN15; SOX4; BMI1; NELFB; PA2G4; NUP62; BRD3; MYBL2; CHD7; ARID4B; SSRP1; HES1; RBM14; PTTG1; RNF138; HMGB2; UBP1; FOXM1; PPRC1; ATF1; EED; ZMYND11; ASH2L; TEAD4; TFAM; STAT5B; NPM1; AEBP1; CIZ1; DEK; HMGB1; ING3; RRN3; ATF5; EDF1; SF1; HDAC1; XRCC6; SMARCA5; PSIP1; PRKDC; KLF6; SRF; RB1; CHD1; KLF7; WWTR1; TFCP2; CNBP; ZNF200; HLTF; SUB1; CSDE1; ELK3; CBX5; NFIB; COPS2; SFPQ; RAN; RERE; CEBPZ; RUVBL2; TRIB3; TRIM28; CTR9; TSC22D2; PURA; FOXN3; NFE2L3; CBFB; ZNF22; RAD21; PBX3; AFF1; ID4; BAZ1A; KLF9; NR2F1; MEIS2; SOX11; MAF; MYBL1; PUF60; HOXC6; EGR3; PPARD