Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17381 Palbociclib GSE70138 MCF10A Human 24h 3.33uM EID0020
Types Number Response transcription factors
Up-regulation 83 MEF2C; PAX8; RFX5; FHL5; ZNF253; ZBED2; LIMD1; PRDM12; FOXN3; PNRC1; JUN; ZFPM2; SP100; LHX6; ZMYND8; ERBB4; ZKSCAN7; TCF4; ZNF117; RXRA; CALCOCO1; MYT1; CSDE1; DDX17; KLF4; CREB3L2; IRF7; CARHSP1; WWC1; AR; TXNIP; ZNF91; SCAND1; EMX2; ZFP36L1; ZNF43; OSR2; SOX17; SALL1; ZNF136; BASP1; MXI1; TCEB2; MEIS1; FOSB; SIAH2; THAP11; CRYM; SIX1; CBX7; ABL1; ZNF430; ZNF264; NR4A2; FOXE1; ESR1; ZNF652; HOXB2; HBP1; ZBTB38; SP110; HLF; MECOM; PAX5; BCL6; NR2F2; FOXF1; BRD2; BTG1; IRF9; NR2F1; FOXG1; ID1; MYT1L; KLF5; ZNF512B; NKX2-1; MAGED1; TRIP6; POU2AF1; ASCL1; CREB1; KDM5D
Down-regulation 48 CCNA2; USP22; GMNN; BRCA1; CENPF; EZH2; FOXM1; NUP62; ZNF45; BRPF1; CIZ1; NFIL3; ILF2; PPRC1; LZTS1; MYBL2; HMGB2; HLTF; SF1; RUVBL2; BLM; BATF3; TRIM28; CBX3; RAD21; PTTG1; NFIB; SMAD6; BRD8; WHSC1; PIR; PITX1; BCL11B; FUBP1; RNF6; ZNF281; STAT4; MYB; TWIST1; ETV5; ZBTB18; INSR; CALR; SAP30; IRX5; SMAD1; GATA6; EGR2