Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17375	Osi-027	GSE70138	MCF10A	Human	24h	3.33uM	EID0020

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	STAT5B; TSC22D3; HMGA2; SOX4; FHL2; EGR1; CDK7; FOXO4; ZNF646; STAT2; FLNA; PPP1R13L; MNT; CALCOCO1; HBP1; BTG1; NRIP1; FOXC1; JARID2; SOX9; TGFB1I1; IRX4; BPTF; NFATC3; KLF7; IRF6; ATF4; PNRC1; STAT5A; GTF3A; PDLIM1; ELF4; ZNF226; TAF10; TCF7L1; ZMIZ1; TRPS1; KLF12; FOXD1; RNF141; NAB2; PBXIP1; PHF20; NR1H3; FOXO3; BCL10; RBPMS; NFAT5; AHR; ST18; GRHL2; ERBB2; TP63; PPARGC1A; ZBTB16; SMAD3; PCGF2; BCL3; KDM5B; CBX7; SMAD2; LPIN2; TXNIP; SIM2; EYA2; AES; ELF3; KLF5; NCOR2; KLF13; MED14; POU4F1; ZFP36L1; FOSL2; TRIM29; TOX; SIX2; HOXC6; KLF6; BRD4; RBPJ; INSR; MAF; TLE1; TGFB1; JUP; ZIC1; HOXC10; HEY1; MECOM; ARID5B; DMTF1
Down-regulation	71	CCNA2; TFDP1; C1QBP; MYCBP; TCERG1; CDK2; SUV39H1; EZH2; DNMT1; BRCA1; RUVBL1; MYBL2; GMNN; GTF2A2; FOSL1; UBP1; FOXM1; PSMC3; RNF138; ZNF232; EED; RBM14; RYBP; TAF5; NUP62; TEAD4; SUB1; CCNC; ZNF473; ENY2; NR2F6; WT1; ILF2; NANOG; CBX5; SLC2A4RG; ZNF200; ING3; PEG3; HMGB3; HMGB2; TFAM; MED21; PTTG1; PBX3; CCNE1; IRF4; BCLAF1; ZNF146; RNF6; HMGB1; RBBP8; CEBPZ; SFPQ; MEIS2; DNMT3B; ZNF43; EMX2; MNDA; ZNF512B; IRX5; MYT1L; TCF21; TLE4; TOB1; MAGED1; SMAD1; ESR1; POU2AF1; PBX1; CREB1