Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17374	Osi-027	GSE70138	MCF10A	Human	24h	10uM	EID0020

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	TSC22D3; HMGA2; MED13; EGR1; SOX4; ZKSCAN1; FHL2; ZMYM2; CDK7; AES; KLF2; BTG1; RELB; CALCOCO1; MED1; ZNF83; BPTF; PNRC1; BTF3; FOXO4; DLX4; PBXIP1; PHF1; CUX1; CARF; NCOR2; ZMIZ1; FOXN3; CIR1; CREBL2; ZNF665; NRIP1; STAT6; REPIN1; TCF7; TCEB2; HIVEP1; HBP1; ZNF160; ERBB2; ZNF91; ING4; DDX5; ZNF623; EZH1; CLOCK; ZNF224; ZNF264; ZNF358; ARID1A; PPP1R13L; CARHSP1; MED12; ZMIZ2; BAZ2A; MNT; JARID2; RUNX1; ZNF611; TGFB1I1; NR1D2; PDLIM1; CBX4; MDM2; HDAC5; INSR; NPAS2; RARA; ERBB4; CRYM; TCF12; NKX3-1; MKL2; FLNA; FOXO3; KDM5B; SMARCC2; TBX3; CHD9; ZNF587; TRIM24; RSF1; JUNB; MXI1; NFATC1; SMAD2; MXD4; AHR; BASP1; CBX7; ZIC1; NCOA3; KLF13; BCL11A; GRHL2; KLF10; IRF9; KAT2B; HLF; SP110; MAGED1; MECOM; SOX11; ZNF652; HEY1; TCF4; SOX9; ZBTB38; ZBTB20; KDM5D; INSM1; TRIB3; MAFB; CREB1; SATB1
Down-regulation	70	CCNA2; MYCBP; TFDP1; EZH2; C1QBP; SUV39H1; BRCA1; CDK2; DNMT1; MYBL2; RUVBL1; PARP1; WDR77; GTF2A2; HDAC2; FOXM1; FOSL1; ADRB2; DR1; PA2G4; PREB; ITGB3BP; EED; GABPA; RNF138; ZNF232; HES1; SSRP1; HMGB2; PTTG1; IRF4; YEATS4; ILF2; XRCC6; CENPF; CCNE1; ZNF45; RUVBL2; PSMC3IP; SUB1; HOXB7; RNF6; PTRF; HMGB1; CBFB; ATF3; WT1; STAT1; NFIB; PRKDC; FOXL2; NFE2; TFAM; MED21; YAP1; EHF; PEG3; PAXBP1; CEBPZ; HHEX; HOXB6; IRX5; HOXC10; RBBP8; ZBED2; SAP30; PURA; HOXC6; MYBL1; HOXB2