Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17362 Bi-2536 GSE70138 MCF10A Human 24h 10uM EID0020
Types Number Response transcription factors
Up-regulation 77 VGLL4; SOX4; NFKBIA; RFX5; HDAC6; MSX1; ID2; TSC22D3; TCEB2; SREBF2; TAF12; MXD4; NR2C1; DRAP1; TCFL5; ABL1; CUX1; RYBP; ATF3; HDAC5; HBP1; LPIN2; SCAND1; TSG101; JARID2; STAT1; PBXIP1; HABP4; IRF7; PNRC1; PHF20; SREBF1; MAGED1; HOXA5; RCOR1; ID1; CRYM; TLE1; TRIM24; MED13; TCF25; HHEX; HMGN3; KLF10; IRF9; DDX5; HEY2; TAF10; CREM; FOXO3; BCL3; IRF6; BRD2; BAZ2B; AFF1; SMARCA1; NR4A1; PIR; BTG1; INSR; ZNF331; KLF13; JUNB; MAF; ID3; TGIF1; JUND; KDM5B; ZSCAN18; INSM1; ZIC1; TSC22D1; HMG20B; CREB1; TXNIP; FOS; BASP1
Down-regulation 119 CCNA2; FOSL1; HMGA2; ADRB2; TCERG1; FHL2; TFDP1; PCBD1; HOXA10; CDK2; SUV39H1; MYC; BRCA1; HOXA1; ATF1; MYBBP1A; CAPN15; GMNN; ZNF232; HNRNPD; RUVBL1; CHAF1B; TBP; DNMT1; EZH2; WDHD1; NUP62; TAF1A; NFKBIB; BATF3; RBL1; CENPF; FOXM1; MYBL2; TAF9; NR2F6; GCFC2; ILF2; PA2G4; GABPB1; RBM14; DEK; E2F8; HMGB2; GATA4; TP63; HDGF; RNF138; PSMC3; DNAJC2; C1QBP; WDR77; IFI16; PSMC3IP; PPRC1; HMGA1; ZNF473; TWIST1; SUZ12; YBX3; BRIP1; ETV6; SMARCA2; TEAD4; EED; CCDC59; CBX3; ABT1; GTF3A; PITX1; APEX1; NPM1; BCLAF1; ZEB1; PITX2; WT1; WHSC1; TCF21; PCGF1; XBP1; FOXF2; ISL1; AEBP1; YEATS4; CEBPD; ZFPM2; KLF9; STAT6; TTF1; FOXD1; HMGB1; SP140L; TGFB1I1; EHF; SMAD3; TBL1XR1; BMI1; PTTG1; MNDA; EYA1; TAF9B; KLF4; ZHX2; MEIS2; ZNF22; MECOM; FOXF1; ZNF551; VDR; SOX11; TLE4; CALR; WWTR1; SAP30; ZNF512B; TRIM29; BHLHE41; MYBL1; SNAI2